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Merck

81210

Sigma-Aldrich

Poly(ethylenglykol)

average Mw 1,500

Synonym(e):

PEG

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About This Item

Lineare Formel:
H(OCH2CH2)nOH
CAS-Nummer:
MDL-Nummer:
UNSPSC-Code:
12352104
PubChem Substanz-ID:
NACRES:
NA.23

product name

Poly(ethylenglykol), average Mw 1,500

Form

solid

Qualitätsniveau

Mol-Gew.

average Mw 1,500

mp (Schmelzpunkt)

45-50 °C

Übergangstemp.

Tm 45-50 °C

Ω-Ende

hydroxyl

α-Ende

hydroxyl

SMILES String

C(CO)O

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

InChIKey

LYCAIKOWRPUZTN-UHFFFAOYSA-N

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Allgemeine Beschreibung

Poly(ethylene glycol) (PEG) is a non-ionic hydrophilic polymer and is available in different molecular weights. It helps in the purification and crystal growth of proteins and nucleic acids. PEG and dextran together result in aqueous polymer two phase system, required for the purification of biological materials. PEG also interacts with cell membrane, thereby resulting in cell fusion.

Anwendung

Poly(ethylene glycol) has been used for histological, histochemical and immunohistochemical evaluation of in vitro cultured beads. It has been used for the fusion of cells.

Sonstige Hinweise

Molecular weight range: 1,400-1,600

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)


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Poly (ethylene glycol) in drug delivery: pros and cons as well as potential alternatives.
Angewandte Chemie (International Edition in English), 49, 6288-6308 (2010)
Poly(Ethylene Glycol) Chemistry: Biotechnical and Biomedical Applications (2013)
I L Konorova et al.
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Artikel

Progress in biotechnology fields such as tissue engineering and drug delivery is accompanied by an increasing demand for diverse functional biomaterials. One class of biomaterials that has been the subject of intense research interest is hydrogels, because they closely mimic the natural environment of cells, both chemically and physically and therefore can be used as support to grow cells. This article specifically discusses poly(ethylene glycol) (PEG) hydrogels, which are good for biological applications because they do not generally elicit an immune response. PEGs offer a readily available, easy to modify polymer for widespread use in hydrogel fabrication, including 2D and 3D scaffold for tissue culture. The degradable linkages also enable a variety of applications for release of therapeutic agents.

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