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Merck

52517

Supelco

1,1,1,3,3,3-Hexafluor-2-propanol

for GC derivatization, LiChropur, ≥99.8%

Synonym(e):

HFP, Hexafluorisopropanol

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10 ML
€ 253,00
10 X 1 ML
€ 267,00
50 ML
€ 969,00

€ 253,00


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10 ML
€ 253,00
10 X 1 ML
€ 267,00
50 ML
€ 969,00

About This Item

Lineare Formel:
(CF3)2CHOH
CAS-Nummer:
Molekulargewicht:
168.04
Beilstein:
1841007
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
12352104
PubChem Substanz-ID:
NACRES:
NA.05

€ 253,00


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Qualität

derivatization grade ((GC derivatization))
for GC derivatization
LiChropur

Qualitätsniveau

Assay

≥99.8% (GC)
≥99.8%

Eignung der Reaktion

reagent type: derivatization reagent
reaction type: Acylations

reagent type: derivatization reagent
reaction type: Esterifications

Methode(n)

gas chromatography (GC): suitable

Brechungsindex

n20/D 1.275 (lit.)

bp

59 °C (lit.)

mp (Schmelzpunkt)

−4 °C (lit.)

Dichte

1.596 g/mL at 25 °C (lit.)

SMILES String

OC(C(F)(F)F)C(F)(F)F

InChI

1S/C3H2F6O/c4-2(5,6)1(10)3(7,8)9/h1,10H

InChIKey

BYEAHWXPCBROCE-UHFFFAOYSA-N

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Allgemeine Beschreibung

Hexafluorisopropanol (HPF) wird allgemein zum Denaturieren des nativen Zustands von Proteinen eingesetzt, stabilisiert aber auch die α-Helixkonformation in ungefalteten Peptiden und Proteinen wie β-Lactoglobulin und Melittin.[1]

Anwendung

Geeignet für die Derivatisierung von Glutaminsäure, Homovanillin-, Iso-Homovanillin- und Dihydroxyphenylessigsäuren sowie Υ-Aminobuttersäure.

Sonstige Hinweise

Reagens für Hexafluorisopropylester, N-Pentafluorpropionyl und Trifluoracetyl.
Size Exclusion Chromatographie in 1,1,1,3,3,3-hexafluoro-2-propanol[2]

Rechtliche Hinweise

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

Piktogramme

Health hazardCorrosion

Signalwort

Danger

Gefahreneinstufungen

Eye Dam. 1 - Repr. 2 - Skin Corr. 1A - STOT RE 2

Lagerklassenschlüssel

8A - Combustible corrosive hazardous materials

WGK

WGK 2

Flammpunkt (°F)

No data available

Flammpunkt (°C)

No data available

Persönliche Schutzausrüstung

Faceshields, Gloves, Goggles


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In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Jie Zhu et al.
Journal of enzyme inhibition and medicinal chemistry, 33(1), 496-506 (2018-02-07)
The cholinergic hypothesis has long been a "polar star" in drug discovery for Alzheimer's disease (AD), resulting in many small molecules and biological drug candidates. Most of the drugs marketed for AD are cholinergic. Herein, we report our efforts in
Sriya Das et al.
ACS applied materials & interfaces, 3(6), 1844-1851 (2011-05-05)
We demonstrate a novel in situ polymerization technique to develop localized polymer coatings on the surface of dispersed pristine graphene sheets. Graphene sheets show great promise as strong, conductive fillers in polymer nanocomposites; however, difficulties in dispersion quality and interfacial
Cooperative a-helix formation of ?-lactoglobulin and melittin induced by hexafluoroisopropanol
Hirota, Nami, Yuji Goto, and Kazuko Mizuno.
Protein Science, 6 (2), 416-421 (1997)
Thomas H Mourey et al.
Journal of chromatography. A, 964(1-2), 169-178 (2002-08-30)
1,1,1,3,3,3-Hexafluoroisopropanol is re-examined as an eluent for size-exclusion chromatography (SEC) of polyesters, nylons, and other polar polymers. It is shown that anomalous SEC behavior reported in previous literature can be eliminated by adding 0.01 M tetraethylammonium nitrate to the eluent.
Alexis Fenyi et al.
Scientific reports, 8(1), 10788-10788 (2018-07-19)
α-synuclein fibrillar polymorphs, Tau and Aß 1-42 fibrillar assemblies have been shown to propagate, amplify and trigger the formation of protein deposits reminiscent of those present within the central nervous system of patients developing synucleinopathies, tauopathies and amyloid plaques after

Questions

1–2 of 2 Questions  
  1. How is shipping temperature determined? And how is it related to the product storage temperature?

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    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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