40733

trans-2-Tetradecenoyl-L-carnitin

analytical standard

• Synonym(e): (2R)-3-Carboxy-N,N,N-trimethyl-2-[[(2E)-1-oxo-2-tetradecen-1-yl]-oxy]-1-propanaminium Inneres Salz, trans-2-Myristenoyl-L-carnitin
• Empirische Formel (Hill-System): C₂₁H₃₉NO₄
• Molekulargewicht: 369.54
• MDL number: MFCD31657520
• UNSPSC Code: 41116107
• NACRES: NA.24

Eigenschaften

• grade: analytical standard
• assay: ≥95.0% (LC/MS)
• optical activity: [α]/D -12±2°, c = 0.1 in methanol
• shelf life: limited shelf life, expiry date on the label
• application(s): clinical testing
• format: neat
• storage temp.: −20°C
• SMILES string: [O-]C(C([H])([H])[C@](OC(/C([H])=C([H])/C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=O)([H])C([H])([H])[N+](C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])=O
• InChI: 1S/C21H39NO4/c1-5-6-7-8-9-10-11-12-13-14-15-16-21(25)26-19(17-20(23)24)18-22(2,3)4/h15-16,19H,5-14,17-18H2,1-4H3/b16-15+/t19-/m1/s1
• InChI key: BUBHHSHBKWNLLG-CLHDZIPGSA-N

Beschreibung

General description

trans-2-Tetradecenoyl-L-carnitine, belonging to the class of acylcarnitines, serves as a specific diagnostic metabolite biomarker, which increases in very long-chain acyl CoA dehydrogenase (VLCAD) deficiency, existing as a long-chain β-oxidation defect in newborns.

Application

trans-2-Tetradecenoyl-L-carnitine may be used as an analytical reference standard in the following:

• Quantification of the analyte in biological samples using high-performance liquid chromatography coupled to tandem mass spectrometry (HPLC/MS/MS).
• Quantification of the analyte in dried blood spots using chip-based nanoelectrospray source coupled with high resolution mass spectrometry (chip-based nanoESI- HRMS) and targeted liquid chromatography-tandem mass spectrometry (LC/MS/MS).

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable