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Merck

142387

Sigma-Aldrich

2,4,6-Trimethylpyridin

ReagentPlus®, 99%

Synonym(e):

2,4,6-Collidin, sym.-Collidin

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€ 26,00
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€ 109,00
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€ 518,00
1 L
€ 785,00

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5 ML
€ 26,00
100 ML
€ 109,00
500 ML
€ 518,00
1 L
€ 785,00

About This Item

Empirische Formel (Hill-System):
C8H11N
CAS-Nummer:
Molekulargewicht:
121.18
Beilstein:
107283
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
12352100
PubChem Substanz-ID:
NACRES:
NA.21

€ 26,00


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Qualitätsniveau

Produktlinie

ReagentPlus®

Assay

99%

Form

liquid

Brechungsindex

n20/D 1.498 (lit.)

bp

171-172 °C (lit.)

mp (Schmelzpunkt)

−43 °C (lit.)

Dichte

0.917 g/mL at 25 °C (lit.)

SMILES String

Cc1cc(C)nc(C)c1

InChI

1S/C8H11N/c1-6-4-7(2)9-8(3)5-6/h4-5H,1-3H3

InChIKey

BWZVCCNYKMEVEX-UHFFFAOYSA-N

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Allgemeine Beschreibung

2,4,6-Trimethylpyridin ist ein Pyridinderivat. Es hat einen pK-Wert von 7,4.[1] Das Produkt kann mit Trifluoriodmethan in Cyclopentanlösung zu einem 1:1-Komplex reagieren. Dieser Komplex wurde mittels NMR-Spektroskopie (NMR: Nuclear Magnetic Resonance) untersucht.[2] Collidingepufferte Osmiumtetroxid-Lösungen werden durch Zugabe von Osmiumtetroxid-Lösung zubereitet. Diese Lösungen werden als Fixiermittel für elektronenmikroskopische Untersuchungen verwendet.[1]
2,4,6-Trimethylpyridin kann mit Kaliumpermanganat zu 2,4,6-Pyridintricarbonsäure oxidiert werden.[3]
Gehinderte Base.

Anwendung

2,4,6-Trimethylpyridin (Collidin, s-Collidin, 2,4,6-Collidin) wurde zur Herstellung einer Bibliothek von N-Acyl-Aminocumarinen mit niedermolekularen N-Acylgruppen verwendet.[4]
Gewebefixiermittel für die Elektronenmikroskopie
Nützliches Lösungsmittel für die Spaltung von gehinderten Estern durch wasserfreies Lithiumjodid.

Rechtliche Hinweise

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

Piktogramme

FlameSkull and crossbones

Signalwort

Danger

Gefahreneinstufungen

Acute Tox. 3 Dermal - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Irrit. 2 - Flam. Liq. 3 - Skin Irrit. 2 - STOT SE 3

Zielorgane

Respiratory system

Lagerklassenschlüssel

3 - Flammable liquids

WGK

WGK 3

Flammpunkt (°F)

131.0 °F - closed cup

Flammpunkt (°C)

55 °C - closed cup

Persönliche Schutzausrüstung

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


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Die Dokumentenbibliothek aufrufen

Synthesis, structure, photoluminescence and magnetic properties of new 3-D lanthanide-pyridine-2, 4, 6-tricarboxylate frameworks
Li C-J, et al.
CrystEngComm, 10(11), 1645-1652 (2008)
Leszek Pazderski et al.
Magnetic resonance in chemistry : MRC, 48(6), 417-426 (2010-05-18)
(1)H, (13)C and (15)N NMR studies of gold(III), palladium(II) and platinum(II) chloride complexes with dimethylpyridines (lutidines: 2,3-lutidine, 2,3lut; 2,4-lutidine, 2,4lut; 3,5-lutidine, 3,5lut; 2,6-lutidine, 2,6lut) and 2,4,6-trimethylpyridine (2,4,6-collidine, 2,4,6col) having general formulae [AuLCl(3)], trans-[PdL(2)Cl(2)] and trans-/cis-[PtL(2)Cl(2)] were performed and the respective
Janet E Del Bene et al.
The journal of physical chemistry. A, 110(3), 1128-1133 (2006-01-20)
Ab initio EOM-CCSD calculations have been performed on 3:1 FH:NH3 complexes at their own optimized MP2/6-31+G(d,p) geometries and at the optimized geometries in the hydrogen-bonding regions of corresponding 3:1 FH:collidine complexes. The isolated gas-phase equilibrium 3:1 FH:NH3 complex has an
Masayoshi Tsubuki et al.
The Journal of organic chemistry, 74(3), 1422-1425 (2008-12-20)
We have found that ruthenium-catalyzed cyclocarbonylation of allenyl alcohols in 2,4,6-collidine under atmospheric pressure of carbon monoxide smoothly proceeds to afford alpha,beta-unsaturated five- and six-membered lactones in moderate to good yields. Furthermore, we have completed a highly stereoselective synthesis of
J L Tomsig et al.
Histochemistry, 89(3), 301-306 (1988-01-01)
In previous work of our laboratory it was demonstrated that collidine (2,4,6-trimethylpyridine) abolishes the core osmiophilia and chromaffin reaction from rat pinal gland and vas deferens nerves. This abolition was apparent when tissues were briefly incubated in collidine or when

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    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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