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Merck

04573

Thiamin -hydrochlorid

tested according to Ph. Eur.

Synonym(e):

Thiamio hydrochloridum, Aneurin -hydrochlorid, Vitamin B1 -hydrochlorid

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Über diesen Artikel

Empirische Formel (Hill-System):
C12H17ClN4OS · HCl
CAS-Nummer:
67-03-8
Molekulargewicht:
337.27
NACRES:
NA.26
PubChem Substance ID:
329747946
eCl@ss:
34058006
UNSPSC Code:
12352209
EC Number:
200-641-8
MDL number:
MFCD00012780
Beilstein/REAXYS Number:
3851771

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InChI key

DPJRMOMPQZCRJU-UHFFFAOYSA-M

InChI

1S/C12H17N4OS.2ClH/c1-8-11(3-4-17)18-7-16(8)6-10-5-14-9(2)15-12(10)13;;/h5,7,17H,3-4,6H2,1-2H3,(H2,13,14,15);2*1H/q+1;;/p-1

SMILES string

CC1=NC(N)=C(C[N+]2=CSC(CCO)=C2C)C=N1.Cl.[Cl-]

biological source

synthetic

Quality Level

200

agency

tested according to Ph. Eur.

assay

98.5-101.0% anhydrous basis

form

solid

mp

250 °C (dec.) (lit.)

solubility

alcohol: soluble 1 gm in 100 ml (95%), alcohol: soluble 1 gm in 315 ml (Absolute), glycerol: soluble 1 gm in 18 ml, water: soluble 1 g/mL, benzene: insoluble, chloroform: insoluble, diethyl ether: insoluble, hexane: insoluble, methanol: very soluble, propylene glycol: soluble

storage temp.

2-8°C

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Dieser Artikel
T4562T4625W332208
Thiamine hydrochloride tested according to Ph. Eur.

Sigma-Aldrich

04573

Thiamine hydrochloride

Thiamine hydrochloride meets USP testing specifications

Sigma-Aldrich

T4562

Thiamine hydrochloride

Thiamine hydrochloride reagent grade, ≥99% (HPLC)

Sigma-Aldrich

T4625

Thiamine hydrochloride

Thiamine hydrochloride ≥98%, FCC, FG

Sigma-Aldrich

W332208

Thiamine hydrochloride

biological source

synthetic

biological source

synthetic (organic)

biological source

synthetic (organic)

biological source

synthetic

agency

USP/NF

agency

USP/NF, meets USP testing specifications

agency

-

agency

meets purity specifications of JECFA

assay

98.5-101.0% anhydrous basis

assay

98.0-102.0%

assay

≥99% (HPLC)

assay

≥98%

form

solid

form

solid

form

powder

form

powder or crystals

mp

250 °C (dec.) (lit.)

mp

250 °C (dec.) (lit.)

mp

250 °C (dec.) (lit.)

mp

250 °C (dec.) (lit.)

solubility

alcohol: soluble 1 gm in 100 ml (95%)

solubility

-

solubility

H2O: 50 mg/mL, clear, colorless

solubility

H2O: 1 g/10 mL, clear, colorless

Application

Thiamine hydrochloride has been used as a keratin salts medium supplement for culturing log-phase fungus.[1] It has also been used as a supplement of VB medium the minimal medium of Vogel and Bonner.[2]

Biochem/physiol Actions

Thiamine hydrochloride is a cheap, non-toxic and efficient catalyst for the synthesis of amidoalkyl naphthols.[3] It inhibits the production of shikonin derivatives by suspension cultures of Lithospermum erythrorhizon.[4] Additionally, thiamine hydrochloride addition to apple juice concentrates reduces its patulin content.[5]
Thiamine hydrochloride is a hydrochloride salt form of thiamine (Vitamin B1). It is crucial for aerobic metabolism, cell growth, transmission of nerve impulses and acetylcholine synthesis.[6]

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H319

Hazard Classifications

Eye Irrit. 2

Lagerklasse

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Hier finden Sie alle aktuellen Versionen:

Analysenzertifikate (COA)

Lot/Batch Number
BCCP0977
BCCN6320
BCCM9897
BCCM2433
BCCL4289

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Die Dokumentenbibliothek aufrufen

G Apodaca et al.
Infection and immunity, 57(10), 3081-3090 (1989-10-01)
Trichophyton rubrum is the most common dermatophyte of humans and normally colonizes the superficial layers of the epidermis (stratum corneum). Several proteinases with a possible role in the metabolism of host proteins have been purified from this fungus. The regulation
Thermodynamics of (solute+ solute) and (solute+ solvent) interactions of homologous series of amino acids with thiamine hydrochloride in aqueous medium at T=(305.15, 310.15, 315.15) K: A volumetric and acoustic approach
Kumar H and Behal I
The Journal of Chemical Thermodynamics, 102, 48-62 (2016)
G E Degnen et al.
Journal of bacteriology, 117(2), 477-487 (1974-02-01)
A mutator gene, mutD5, whose phenotype is conditional, has been identified in Escherichia coli. By P1 transduction it has been shown to lie at about 5.7 min on the chromosome, being co-transduced with proA and argF. In rich medium, streptomycin-
Thiamine hydrochloride as an efficient catalyst for the synthesis of amidoalkyl naphthols.
Min Lei
Tetrahedron Letters, 50, 6393-6397 (2009)
Y Fujita et al.
Plant cell reports, 1(2), 61-63 (1981-12-01)
An excellent new medium was developed for the production of shikonin derivatives by suspension cultures of Lithospermum erythrorhizon. We investigated the effects of all the components of White's medium on the production of these derivatives. Nitrate, phosphate, copper, sulfate and
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