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| Packungsgröße | SKU | Verfügbarkeit | Preis |
|---|---|---|---|
| 100 μL | Warenkorb auf Verfügbarkeit prüfen | € 337,00 |
Über diesen Artikel
biological source
mouse
Quality Level
conjugate
unconjugated
antibody form
ascites fluid
antibody product type
primary antibodies
clone
SP10, monoclonal
species reactivity
rat, hamster, salamander, pig, human
manufacturer/tradename
Chemicon®
technique(s)
immunohistochemistry: suitable, western blot: suitable
isotype
IgM
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... VAMP1(6843)
Immunogen
Application
Western blotting at 1:100-1:10,000.
Optimal working dilutions must be determined by the end user.
Neuroscience
Synapse & Synaptic Biology
Biochem/physiol Actions
Physical form
Preparation Note
Other Notes
Legal Information
Disclaimer
1 of 1
Dieser Artikel | |||
|---|---|---|---|
| conjugate unconjugated | conjugate unconjugated | conjugate unconjugated | conjugate unconjugated |
| species reactivity rat, hamster, salamander, pig, human | species reactivity human, mouse, rat, rabbit, bovine, dog, sheep, horse, guinea pig | species reactivity rat, mouse | species reactivity human |
| biological source mouse | biological source rabbit | biological source rabbit | biological source rabbit |
| Gene Information human ... VAMP1(6843) | Gene Information human ... VAMP7(6845) | Gene Information human ... VAMP1(6843) | Gene Information human ... VAMP7(6845) |
| clone SP10, monoclonal | clone polyclonal | clone monoclonal | clone polyclonal |
| antibody form ascites fluid | antibody form affinity isolated antibody | antibody form - | antibody form affinity isolated antibody |
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Lagerklasse
10 - Combustible liquids
Analysenzertifikate (COA)
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Verwandter Inhalt
Glutamate is an excitatory neurotransmitter found in the synaptic vesicles of glutamatergic synapses. The post-synaptic neurons in these synapses contain ionotropic and metabotropic glutamate receptors. Glutamate binds to AMPA (α-amino-3-hydroxy-5- methylisoxazole-4-propionic acid) subtype glutamate receptors, leading to sodium influx into the post-synaptic cell and resulting in neuronal excitability and synaptic transmission. The NMDA (N-methyl-d-aspartate) subtype glutamate receptors, on the other hand, regulate synaptic plasticity, and can influence learning and memory. The metabotropic g-protein coupled mGluRs modulate downstream calcium signaling pathways and indirectly influence the synapse’s excitability. The synaptic architecture includes intracellular scaffolding proteins (PSD-95, GRIP), intercellular cell adhesion molecules (NCAMs, N-Cadherins), and a variety of signaling proteins (CaMKII/PKA, PP1/PP2B). Processes critical for synaptic transmission and plasticity are influenced by these molecules and their interactions. When the function of these molecules is disrupted, it leads to synaptic dysfunction and degeneration, and can contribute to dementia as seen in Alzheimer’s disease.
Global Trade Item Number
| SKU | GTIN |
|---|---|
| MAB333 | 04053252664458 |



