Direkt zum Inhalt
Merck

Fortfahren mit

MAB333

Anti-Synaptobrevin Antibody, clone SP10

ascites fluid, clone SP10, Chemicon®

Synonym(e):

VAMP

Anmelden zur Ansicht der Organisations- und Vertragspreise.

Größe auswählen

Ansicht ändern
PackungsgrößeSKUVerfügbarkeitPreis
100 μL
Warenkorb auf Verfügbarkeit prüfen
€ 337,00

Über diesen Artikel

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
SP10, monoclonal
Application:
IHC, WB
Citations:
12

€ 337,00


Warenkorb auf Verfügbarkeit prüfen

Großbestellung anfragen
Technischer Dienst
Benötigen Sie Hilfe? Unser Team von erfahrenen Wissenschaftlern ist für Sie da.
Unterstützung erhalten


biological source

mouse

Quality Level

conjugate

unconjugated

antibody form

ascites fluid

antibody product type

primary antibodies

clone

SP10, monoclonal

species reactivity

rat, hamster, salamander, pig, human

manufacturer/tradename

Chemicon®

technique(s)

immunohistochemistry: suitable, western blot: suitable

isotype

IgM

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... VAMP1(6843)

Immunogen

Crude synaptic immunoprecipitate (Human).

Application

Anti-Synaptobrevin Antibody, clone SP10 is an antibody against Synaptobrevin for use in WB, IH.
Immunohistochemistry at >1:25.

Western blotting at 1:100-1:10,000.

Optimal working dilutions must be determined by the end user.
Research Category
Neuroscience
Research Sub Category
Synapse & Synaptic Biology

Biochem/physiol Actions

Synaptobrevin [VAMP]. MAB333 reacts with VAMP-1 and VAMP-2 fusion protein expressed in bacterial system.

Physical form

Liquid, contains sodium azide.

Preparation Note

Maintain frozen at -20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.

Other Notes

Replaces: AB5863P

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Ähnliche Artikel vergleichen

Vollständigen Vergleich anzeigen

Unterschiede anzeigen

1 of 1

Dieser Artikel
SAB2105695SAB5701461HPA036733
conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

species reactivity

rat, hamster, salamander, pig, human

species reactivity

human, mouse, rat, rabbit, bovine, dog, sheep, horse, guinea pig

species reactivity

rat, mouse

species reactivity

human

biological source

mouse

biological source

rabbit

biological source

rabbit

biological source

rabbit

Gene Information

human ... VAMP1(6843)

Gene Information

human ... VAMP7(6845)

Gene Information

human ... VAMP1(6843)

Gene Information

human ... VAMP7(6845)

clone

SP10, monoclonal

clone

polyclonal

clone

monoclonal

clone

polyclonal

antibody form

ascites fluid

antibody form

affinity isolated antibody

antibody form

-

antibody form

affinity isolated antibody


Still not finding the right product?

Probieren Sie unser Produkt-Auswahlhilfe, um Ihre Auswahl einzugrenzen


Lagerklasse

10 - Combustible liquids



Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

Besitzen Sie dieses Produkt bereits?

In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen


Verwandter Inhalt

Glutamate is an excitatory neurotransmitter found in the synaptic vesicles of glutamatergic synapses. The post-synaptic neurons in these synapses contain ionotropic and metabotropic glutamate receptors. Glutamate binds to AMPA (α-amino-3-hydroxy-5- methylisoxazole-4-propionic acid) subtype glutamate receptors, leading to sodium influx into the post-synaptic cell and resulting in neuronal excitability and synaptic transmission. The NMDA (N-methyl-d-aspartate) subtype glutamate receptors, on the other hand, regulate synaptic plasticity, and can influence learning and memory. The metabotropic g-protein coupled mGluRs modulate downstream calcium signaling pathways and indirectly influence the synapse’s excitability. The synaptic architecture includes intracellular scaffolding proteins (PSD-95, GRIP), intercellular cell adhesion molecules (NCAMs, N-Cadherins), and a variety of signaling proteins (CaMKII/PKA, PP1/PP2B). Processes critical for synaptic transmission and plasticity are influenced by these molecules and their interactions. When the function of these molecules is disrupted, it leads to synaptic dysfunction and degeneration, and can contribute to dementia as seen in Alzheimer’s disease.


G Bonanno et al.
British journal of pharmacology, 129(8), 1780-1786 (2000-04-26)
The release of [(3)H]-dopamine ([(3)H]-DA) from human neocortex nerve terminals was studied in synaptosomes prepared from brain specimens removed in neurosurgery and exposed during superfusion to different releasing stimuli. Treatment with 15 mM KCl, 100 microM 4-aminopyridine, 1 microM ionomycin
Huayu Qi et al.
Molecular biology of the cell, 13(2), 530-541 (2002-02-21)
The zona pellucida (ZP) is a highly organized extracellular coat that surrounds all mammalian eggs. The mouse egg ZP is composed of three glycoproteins, called mZP1-3, that are synthesized, secreted, and assembled into a ZP exclusively by growing oocytes. Here
M Raiteri et al.
Journal of neurochemistry, 74(1), 423-431 (2000-01-05)
Small molecules present during brain tissue homogenization are known to be entrapped within subsequently isolated synaptosomes. We have revisited this technique in view of its systematic utilization to incorporate into nerve endings impermeant probes of large size. Rat neocortical synaptosomes



Global Trade Item Number

SKUGTIN
MAB33304053252664458

Questions

Reviews

No rating value

Active Filters