AB2233
Anti-Galanin Antibody
serum, from rabbit
Synonym(e):
galanin prepropeptide, galanin-message-associated peptide, galanin-related peptide
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100 μL
€ 385,00
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100 μL
€ 385,00
About This Item
UNSPSC-Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Empfohlene Produkte
Biologische Quelle
rabbit
Qualitätsniveau
Antikörperform
serum
Antikörper-Produkttyp
primary antibodies
Klon
polyclonal
Speziesreaktivität
rat
Speziesreaktivität (Voraussage durch Homologie)
mouse, boar, human
Methode(n)
immunohistochemistry: suitable (paraffin)
NCBI-Hinterlegungsnummer
UniProt-Hinterlegungsnummer
Versandbedingung
wet ice
Posttranslationale Modifikation Target
unmodified
Angaben zum Gen
human ... GAL(51083)
Allgemeine Beschreibung
Galanin is a neuropeptide which is not a member of any known family of neuropeptides, despite repeated efforts to discover related peptides. Its actions are mediated via Gi-protein-coupled receptors (GPCR’s) and ion channels, usually producing inhibition of secretion of a transmitter or hormone in the nervous and endocrine system. In many respects, these inhibitory actions of galanin remind us of those of gamma-aminobutyric acid (GABA) and of neuropeptide Y (NPY). Galanin coexists with GABA, noradrenaline, 5-hydroxytryptamine (5-HT), and NPY in several regions of the brain. Galanin and it’s receptor are over expressed in limbic region of the brain in patients suffering from Alzheimer′s disease. However it is not clear whether galanin exacerbates or is a protective response to the disease.
Spezifität
Cat. # AB2233 recognizes Galanin
Reactivity with other species has not been determined.
Immunogen
Synthetic Linear Peptide
Anwendung
Research Category
Neurowissenschaft
Neurowissenschaft
Research Sub Category
Neurochemie & Neurotrophine
Neurochemie & Neurotrophine
Detect Galanin using this Anti-Galanin Antibody validated for use in IH(P).
Qualität
Routinely evaluated by Immunhistochemistry on rat cerebellum tissue.
Zielbeschreibung
13.3 kDa
Physikalische Form
Serum with 0.05% NaN3
Lagerung und Haltbarkeit
Maintain at -20°C for up to 1 year from date of receipt.
Hinweis zur Analyse
Control
Rat Cerebellum Tissue
Rat Cerebellum Tissue
Haftungsausschluss
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Lagerklassenschlüssel
10 - Combustible liquids
WGK
WGK 1
Analysenzertifikate (COA)
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The Journal of neuroscience : the official journal of the Society for Neuroscience, 41(42), 8725-8741 (2021-09-01)
Galanin, one of the most inducible neuropeptides, is widely present in developing brains, and its expression is altered by pathologic events (e.g., epilepsy, ischemia, and axotomy). The roles of galanin in brain development under both normal and pathologic conditions have
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Intraovarian distribution and density of nerve fibres immunoreactive (IR) to protein gene product 9.5 (PGP 9.5) and containing dopamine-β-hydroxylase (DβH), neuropeptide Y (NPY), somatostatin (SOM), galanin (GAL) were determined. From day 4 of the first oestrous cycle to day 20
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