8.53007

Boc-Asn(Xan)-OH

Novabiochem^®

• Synonym(e): Boc-Asn(Xan)-OH, N-α-t.-Boc-N-β-xanthyl-L-asparagine
• Empirische Formel (Hill-System): C₂₂H₂₄N₂O₆
• CAS-Nummer: 65420-40-8
• Molekulargewicht: 412.44
• UNSPSC Code: 12352209
• NACRES: NA.22
• MDL number: MFCD00066157

Eigenschaften

• Quality Segment: 200
• product line: Novabiochem^®
• assay: ≥98% (TLC), ≥98.0% (HPLC)
• form: powder
• reaction suitability: reaction type: Boc solid-phase peptide synthesis
• manufacturer/tradename: Novabiochem^®
• application(s): peptide synthesis
• functional group: amide
• storage temp.: 2-30°C
• SMILES string: N([C@@H](CC(=O)NC1c2c(cccc2)Oc3c1cccc3)C(=O)O)C(=O)OC(C)(C)C
• InChI: 1S/C22H24N2O6/c1-22(2,3)30-21(28)23-15(20(26)27)12-18(25)24-19-13-8-4-6-10-16(13)29-17-11-7-5-9-14(17)19/h4-11,15,19H,12H2,1-3H3,(H,23,28)(H,24,25)(H,26,27)/t15-/m0/s1
• InChI key: YMGDQLXBNMRJMR-HNNXBMFYSA-N

Beschreibung

General description

Standard building block for introduction of asparagine residues in Boc SPPS. Its use avoids the risk of cyano alanine formation when using uronium coupling reagents

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Boc SPPS

Analysis Note

Colour (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Optical rotation α 25/D (c=1 in methanol): +7.5 - +10.5 °
Purity (TLC(011A)): ≥ 98 %
Purity (TLC(0811)): ≥ 98 %
Assay (HPLC, area%): ≥ 98.0 % (a/a)
Solubility (1 mmole in 2 ml DMF): clearly soluble

To see the solvent systems used for TLC of Novabiochem^® products please click here.

Other Notes

Replaces: 04-12-0022

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable