This product is only tested in 50% acetic acid at 10 mg/mL. Literature indicates that solubility in DMSO is possible. Further research is highly recommended.
444221
MMP-1/MMP-9 Substrate
≥95% (HPLC), Fluorescent MMP Substrate, solid
Synonym(e):
MMP-1/MMP-9 Substrate, Fluorogenic
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| Größe/SKU | Verfügbarkeit | Preis |
|---|---|---|
1 mg | Warenkorb auf Verfügbarkeit prüfen | € 504,00 |
Über diesen Artikel
Empirische Formel (Hill-System):
C49H68N14O12S
Molekulargewicht:
1077.22
UNSPSC Code:
12352200
NACRES:
NA.77
Assay:
≥95% (HPLC)
Form:
solid
Storage condition:
OK to freeze, protect from light
Technischer Dienst
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Unterstützung erhaltenProduktname
MMP-1/MMP-9 Substrate, Fluorogenic, An excellent quenched fluorescence substrate for MMP-1 and MMP-9.
Quality Segment
assay
≥95% (HPLC)
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, protect from light
color
yellow
solubility
50% acetic acid: 10 mg/mL
fluorescence
λex ~365 nm, λem ~450 nm
shipped in
ambient
storage temp.
−20°C
General description
An excellent quenched fluorescence substrate for MMP-1 and MMP-9 (excitation maximum: 365 nm; emission maximum: 450 nm). Both enzymes cleave this substrate between Gly and Cys(Me), liberating a fluorescent cleavage product. Suitable for inhibitor screening and determining Ki values. Excitation max: ~365 nm; emission max: ~450 nm.
Biochem/physiol Actions
Cell permeable: no
Primary Target
MMP-1, MMP-9
MMP-1, MMP-9
Product does not compete with ATP.
Reversible: no
Packaging
Packaged under inert gas
Other Notes
Bickett, D.M., et al. 1993. Anal. Biochem. 212, 58.
{DNP-Pro-Cha-Gly-Cys(Me)-His-Ala-Lys(N-Me-Abz)-NH₂[Cha = β-cyclohexylalanyl; Abz = 2-aminobenzoyl (anthraniloyl)]
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
1 of 1
Dieser Artikel | |||
|---|---|---|---|
| description An excellent quenched fluorescence substrate for MMP-1 and MMP-9. | description A fluorogenic substrate for both the 72 kDa human fibroblast gelatinase (HFG; MMP-2) and the 92 kDa human neutrophil gelatinase (HNG; MMP-9). | description A quenched fluorescence substrate for MMP-2 (gelatinase A; kcat/Km = 3.97 x 10⁵ M⁻¹s⁻¹). | description A fluorogenic substrate probe useful for assaying trypsin-like activity of proteasome. |
| assay ≥95% (HPLC) | assay ≥95% (HPLC) | assay ≥95% (HPLC) | assay ≥98% (HPLC) |
| form solid | form solid | form lyophilized solid | form solid |
| manufacturer/tradename Calbiochem® | manufacturer/tradename Calbiochem® | manufacturer/tradename Calbiochem® | manufacturer/tradename Calbiochem® |
| Quality Level 100 | Quality Level 100 | Quality Level 100 | Quality Level 100 |
| storage temp. −20°C | storage temp. −20°C | storage temp. −20°C | storage temp. −20°C |
| storage condition protect from light, OK to freeze | storage condition protect from light, OK to freeze | storage condition desiccated, protect from light, OK to freeze | storage condition protect from light, OK to freeze |
Lagerklasse
11 - Combustible Solids
Was ist los?
WGK 1
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
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can i solve this substrate in DMSO or DMF
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