3542

Glutathion, oxidiert, freie Säure

≥95% (HPLC), Antioxidant, solid

• Synonym(e): Glutathion, oxidiert, freie Säure, Zyklisches (γ-Glu-Cys-Gly)₂, GSSG
• Empirische Formel (Hill-System): C₂₀H₃₂N₆O₁₂S₂
• CAS-Nummer: 27025-41-8
• Molekulargewicht: 612.63
• UNSPSC Code: 12352209
• NACRES: NA.25
• MDL number: MFCD00063106

Eigenschaften

• Produktname: Glutathion, oxidiert, freie Säure, Glutathione, Oxidized, Free Acid, CAS 27025-41-8, forms a "redox buffer" in physiological systems in the presence of reduced glutathione.
• SMILES string: S(SCC(NC(=O)CCC(N)C(=O)O)C(=O)NCC(=O)O)CC(NC(=O)CCC(N)C(=O)O)C(=O)NCC(=O)O
• InChI: 1S/C20H32N6O12S2/c21-9(19(35)36)1-3-13(27)25-11(17(33)23-5-15(29)30)7-39-40-8-12(18(34)24-6-16(31)32)26-14(28)4-2-10(22)20(37)38/h9-12H,1-8,21-22H2,(H,23,33)(H,24,34)(H,25,27)(H,26,28)(H,29,30)(H,31,32)(H,35,36)(H,37,38)
• InChI key: YPZRWBKMTBYPTK-UHFFFAOYSA-N
• description: RTECS - MC0556500; Merck USA index - 14, 4475
• assay: ≥95% (HPLC)
• form: solid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze
• color: white
• solubility: water: 1 mg/mL; DMF: 10 mg/mL; ethanol: 5 mg/mL
• shipped in: ambient
• storage temp.: 2-8°C
• Quality Level: 200

Beschreibung

Disclaimer

Toxizität: Reizstoff (B)

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Features and Benefits

• Cell permeable: no
• Product does not compete with ATP
• Reversible: no

General description

Glutathione disulfide (GSSG) is the oxidized form of glutathione (GSH), an antioxidant containing cysteine, glycine, and glutamic acid. [1]GSSG is composed of two reduced GSH molecules linked by a disulfide bond.[2] GSSG plays an essential role in cellular redox balance, and protection against oxidative stress. The reduced glutathione-to-oxidized glutathione (GSH/GSSG) ratio serves as an indicator of oxidative stress.[3] It is involved in various biochemical processes, including the regulation of immune function and metabolism.[4]

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable