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Merck

850481C

Avanti

16:0-18:0 (9-10BR) PC

1-palmitoyl-2-(9,10-dibromo)stearoyl-sn-glycero-3-phosphocholine, chloroform

Synonym(e):

1-hexadecanoyl-2-(9,10-dibromooctadecanoyl)-sn-glycero-3-phosphocholine

Anmeldenzur Ansicht organisationsspezifischer und vertraglich vereinbarter Preise


About This Item

Empirische Formel (Hill-System):
C42H82NO8PBr2
CAS-Nummer:
Molekulargewicht:
919.88
UNSPSC-Code:
12352211
NACRES:
NA.25

Assay

>99% (TLC)

Form

liquid

Verpackung

pkg of 1 × 1 mL (850481C-10mg)

Hersteller/Markenname

Avanti Research - A Croda Brand 850481C

Konzentration

10 mg/mL (850481C-10mg)

Versandbedingung

dry ice

Lagertemp.

−20°C

Allgemeine Beschreibung

16:0-18:0 (9-10BR) PC (1-palmitoyl-2-(9,10-dibromo) stearoyl-sn-glycero-3-phosphocholine) is a brominated phosphatidylcholine lipid. This lipid is stable for one year.

Anwendung

16:0-18:0 (9-10BR) PC (1-palmitoyl-2-(9,10-dibromo) stearoyl-sn-glycero-3-phosphocholine) has been used in large unilamellar vesicles (LUVs) and small unilamellar vesicles (SUVs) for fluorescence quenching. It has also been used to prepare large unilamellar vesicles (LUV) for liposome co-sedimentation assay. It may be used as a component in large unilamellar liposomes for parallax analysis and in lipid vesicle preparation for tryptophan (Trp) penetration depth experiments/bromine quenching experiments.

Biochem./physiol. Wirkung

16:0-18:0 (9-10BR) PC (1-palmitoyl-2-(9,10-dibromo) stearoyl-sn-glycero-3-phosphocholine) can act as a deep quencher.

Verpackung

5 mL Clear Glass Sealed Ampule (850481C-10mg)

Rechtliche Hinweise

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Piktogramme

Skull and crossbonesHealth hazard

Signalwort

Danger

Gefahreneinstufungen

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Zielorgane

Central nervous system

WGK

WGK 3


Analysenzertifikate (COA)

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Die Dokumentenbibliothek aufrufen

Caroline Montagner et al.
Biochemistry, 46(7), 1878-1887 (2007-01-26)
During intoxication of a cell, the translocation (T) domain of the diphtheria toxin helps the passage of the catalytic domain across the membrane of the endosome into the cytoplasm. We have investigated the behavior of the N-terminal region of the
Thai Leong Yap et al.
The Journal of biological chemistry, 290(2), 744-754 (2014-11-28)
Mutations in glucocerebrosidase (GCase), the enzyme deficient in Gaucher disease, are a common genetic risk factor for the development of Parkinson disease and related disorders, implicating the role of this lysosomal hydrolase in the disease etiology. A specific physical interaction
Kwok-Ho Lam et al.
Cell reports, 30(8), 2526-2539 (2020-02-27)
Botulinum neurotoxin (BoNT) is one of the most acutely lethal toxins known to humans, and effective treatment for BoNT intoxication is urgently needed. Single-domain antibodies (VHH) have been examined as a countermeasure for BoNT because of their high stability and
John M Harrington et al.
PloS one, 7(9), e44384-e44384 (2012-09-13)
The bloodstream developmental forms of pathogenic African trypanosomes are uniquely susceptible to killing by small hydrophobic peptides. Trypanocidal activity is conferred by peptide hydrophobicity and charge distribution and results from increased rigidity of the plasma membrane. Structural analysis of lipid-associated
Candace M Pfefferkorn et al.
Biochimica et biophysica acta, 1848(11 Pt A), 2821-2828 (2015-08-25)
Apolipoproteins are essential human proteins for lipid metabolism. Together with phospholipids, they constitute lipoproteins, nm to μm sized particles responsible for transporting cholesterol and triglycerides throughout the body. To investigate specific protein-lipid interactions, we produced and characterized three single-Trp containing

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