QBD10119

Acid-dPEG^®₉-NHS ester

• Synonym(e): Polyethylene glycol
• Empirische Formel (Hill-System): C₂₆H₄₅NO₁₅
• Molekulargewicht: 611.63
• MDL-Nummer: MFCD28064339
• UNSPSC-Code: 12352106
• PubChem Substanz-ID: 329823880
• NACRES: NA.22

Eigenschaften

• Assay: >90%
• Form: solid or viscous liquid
• Eignung der Reaktion: reagent type: cross-linking reagent; reactivity: amine reactive
• Funktionelle Gruppe: NHS ester; carboxylic acid
• Polymerarchitektur: shape: linear; functionality: heterobifunctional
• Versandbedingung: ambient
• Lagertemp.: −20°C
• SMILES String: OC(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(ON1C(CCC1=O)=O)=O)=O
• InChI: 1S/C26H45NO15/c28-23-1-2-24(29)27(23)42-26(32)4-6-34-8-10-36-12-14-38-16-18-40-20-22-41-21-19-39-17-15-37-13-11-35-9-7-33-5-3-25(30)31/h1-22H2,(H,30,31)
• InChIKey: BJOKQEMLFQBOQZ-UHFFFAOYSA-N

Beschreibung

Leistungsmerkmale und Vorteile

Acid-dPEG^®₉-NHS ester is a unique heterobifunctional dPEG^® crosslinking product which allows conjugation to two different moieties, each containing free amines. Because the single molecular weight dPEG^® spacers contain an N-hydroxysuccinimide ester only on one end of the spacer, greater control of the conjugation reaction can be maintained. The free acid end of the spacer can be left unreacted to modify the surface properties of the molecule to which it is conjugated, or the free acid end can be activated and conjugated to a different group at a later time. The dPEG^® spacers provide precise spacing/distance control, and the dPEG^® itself provides the well-known benefits of increased water solubility; decreased immunogenicity; protection from proteolysis; increased hydrodynamic volume; and increased serum half-life.

Rechtliche Hinweise

Products Protected under U.S. Patents # 7,888,536 B2

dPEG is a registered trademark of Quanta BioDesign

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable