N5893

(±)-Naringenin

≥95%

• Synonym(e): (±)-2,3-Dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-on, 4′,5,7-Trihydroxyflavanon
• Empirische Formel (Hill-System): C₁₅H₁₂O₅
• CAS-Nummer: 67604-48-2
• Molekulargewicht: 272.25
• EG-Nummer: 266-769-1
• MDL-Nummer: MFCD00006844
• UNSPSC-Code: 12352100
• PubChem Substanz-ID: 57654457
• NACRES: NA.22

Eigenschaften

• Assay: ≥95%
• Form: powder
• mp (Schmelzpunkt): 247-250 °C (lit.)
• SMILES String: OC1=CC=C(C=C1)C(C2)OC3=CC(O)=CC(O)=C3C2=O
• InChI: 1S/C15H12O5/c16-9-3-1-8(2-4-9)13-7-12(19)15-11(18)5-10(17)6-14(15)20-13/h1-6,13,16-18H,7H2
• InChIKey: FTVWIRXFELQLPI-UHFFFAOYSA-N
• Angaben zum Gen: human ... CYP1A2(1544)

Beschreibung

Anwendung

(±)-Naringenin, a polyphenolic material, is used to prepare nickel(II) naringenin-oxime complex, which can be used as a catalyst for Mizoroki−Heck cross-coupling reaction. It has been used as a hypochlorite scavenger to prevent the formation of chloramines from oxidation of hypochlorite in the human serum albumin. It induces apoptosis in human pancreatic cancer SNU-213 cells. It also shows cytotoxic effects on various human cancer cells such as breast, cervix, stomach, colon and liver cancer cells.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H302
• P-Sätze: P264 - P270 - P301 + P312 - P501
• Gefahreneinstufungen: Acute Tox. 4 Oral
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves