CF0041

Urea crosslinker – C₄-arm, NHS ester (DSBU, BuUrBU)

• Synonym(e): 1,1′-Bis(2,5-dioxo-1-pyrrolidinyl) 4,4′-(carbonyldiimino)bis[butanoate], Disuccinimidyldibutyric urea
• Lineare Formel: C₁₇H₂₂N₄O₉
• CAS-Nummer: 1240387-33-0
• UNSPSC Code: 12161502
• NACRES: NA.22
• MDL number: MFCD30738322
• Form: solid

Eigenschaften

• form: solid
• reaction suitability: reaction type: C-C Bond Formation, reagent type: cross-linking reagent
• SMILES string: N2(C(=O)CCC2=O)OC(=O)CCCNC(=O)NCCCC(=O)ON1C(=O)CCC1=O
• InChI: 1S/C17H22N4O9/c22-11-5-6-12(23)20(11)29-15(26)3-1-9-18-17(28)19-10-2-4-16(27)30-21-13(24)7-8-14(21)25/h1-10H2,(H2,18,19,28)
• InChI key: XZSQCCZQFXUQCY-UHFFFAOYSA-N

Beschreibung

Application

The ureido-4,4´-dibutyric acid bis(hydroxysuccinimide) ester, also known as DSBU or BuUrBU, is the longest version of MS-cleavable urea-based lysine-lysine reactive homobifunctional cross-linkers, featuring a C₄-arm. At neutral or slightly basic pH, it irreversibly crosslinks the neighbouring lysine groups. The presence of the symmetrical urea moiety which is prone to collision-induced dissociation allows for the unambiguous distinguishing of crosslinks in tandem CID-MS experiments.

Legal Information

Product of CF Plus Chemicals.

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable