748188

Bis(2,2,6,6-tetramethylpiperidinyl)zinc, lithium chloride, magnesium chloride complex solution

in THF/toluene

• Lineare Formel: C₁₈H₃₆N₂Zn · xMgCl₂ · xLiCl
• UNSPSC-Code: 12352103
• NACRES: NA.22

Eigenschaften

• Form: liquid
• Zusammensetzung: Bis(2,2,6,6-tetramethylpiperidinyl)zinc, ~12 wt. % ; LiCl, 2-4% ; MgCl₂, 6-9% ; THF/toluene, ca. 90:10 (solvent)
• Konzentration: in THF/toluene
• Dichte: 0.991 g/mL at 25 °C

Beschreibung

Allgemeine Beschreibung

Bis(2,2,6,6-tetramethylpiperidinyl)zinc,lithium chloride, magnesium chloride complex solution is an organozinc reagentextensively used in C-C bond forming,Negishi coupling, Michael additions, Cu(I)-promoted reactions, and electrophilic amination reactions.

Anwendung

Bis(2,2,6,6-tetramethylpiperidinyl)zinc, lithium chloride, magnesium chloride complex solution can be used as a base for the:

• Regioselective zincation of pyridines and related azines to synthesize zincated pyridines and azines.(1)
• Chemoselective direct zincation of arenes and heteroarenes to synthesize polyfunctional aryl and heteroaryl zinc reagents.
• Regioselective zincation of thiazoles to synthesize zincated thiazoles, which readily reacts with various electrophiles to form highly functionalized thiazoles.

Sicherheitshinweise

• Piktogramme: GHS02,GHS08,GHS05,GHS07
• Signalwort: Danger
• H-Sätze: H225,H314,H335,H336,H351,H361d
• P-Sätze: P202 - P210 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Gefahreneinstufungen: Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - Repr. 2 - Skin Corr. 1B - STOT SE 3
• Zielorgane: Central nervous system, Respiratory system
• Zusätzliche Gefahrenhinweise: EUH014,EUH019
• Lagerklassenschlüssel: 3 - Flammable liquids
• WGK: WGK 3
• Flammpunkt (°F): 5.0 °F
• Flammpunkt (°C): -15 °C