638013

4-Diphenylphosphanylbenzoesäure, 2-(Trimethylsilyl)ethylester -Lösung

0.5 M in THF

• Empirische Formel (Hill-System): C₂₄H₂₇O₂PSi
• CAS-Nummer: 566190-45-2
• Molekulargewicht: 406.53
• MDL-Nummer: MFCD07369722
• UNSPSC-Code: 12352108
• PubChem Substanz-ID: 24882904

Eigenschaften

• Eignung der Reaktion: reaction type: Buchwald-Hartwig Cross Coupling Reaction; reaction type: Heck Reaction; reaction type: Hiyama Coupling; reaction type: Negishi Coupling; reaction type: Sonogashira Coupling; reaction type: Stille Coupling; reaction type: Suzuki-Miyaura Coupling; reagent type: ligand
• Konzentration: 0.5 M in THF
• Dichte: 0.925 g/mL at 25 °C
• Funktionelle Gruppe: phosphine
• SMILES String: C[Si](C)(C)CCOC(=O)c1ccc(cc1)P(c2ccccc2)c3ccccc3
• InChI: 1S/C24H27O2PSi/c1-28(2,3)19-18-26-24(25)20-14-16-23(17-15-20)27(21-10-6-4-7-11-21)22-12-8-5-9-13-22/h4-17H,18-19H2,1-3H3
• InChIKey: QTYUNPJLGFKKRV-UHFFFAOYSA-N

Beschreibung

Anwendung

4-Diphenylphosphanyl-benzoic acid 2-trimethylsilanyl-ethyl ester (DPPBE) was developed as an efficient alternative to triphenylphosphine in the Mitsunobu reaction since the phosphine oxide formed during the reaction can be easily removed during workup.

Reagent for:

• Synthesis of alkenes
• Methylation of aldehydes
• Mitsunobu reactions

Sicherheitshinweise

• Piktogramme: GHS02,GHS08,GHS07
• Signalwort: Danger
• H-Sätze: H225,H319,H335,H351
• P-Sätze: P210 - P280 - P305 + P351 + P338 - P370 + P378 - P403 + P235
• Gefahreneinstufungen: Carc. 2 - Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Zusätzliche Gefahrenhinweise: EUH019
• Lagerklassenschlüssel: 3 - Flammable liquids
• WGK: WGK 3
• Flammpunkt (°F): -4.0 °F - closed cup
• Flammpunkt (°C): -20 °C - closed cup