47622

Fmoc-Thr(tBu)-OH

≥98.0% (HPLC), for peptide synthesis

• Synonym(e): Fmoc-O-tert.-butyl-L-threonin
• Empirische Formel (Hill-System): C₂₃H₂₇NO₅
• CAS-Nummer: 71989-35-0
• Molekulargewicht: 397.46
• Beilstein: 4581133
• EG-Nummer: 276-261-1
• MDL-Nummer: MFCD00077075
• UNSPSC-Code: 12352209
• eCl@ss: 32160406
• PubChem Substanz-ID: 57651042
• NACRES: NA.26

Eigenschaften

• Produktbezeichnung: Fmoc-Thr(tBu)-OH, ≥98.0% (HPLC)
• Qualitätsniveau: 100
• Assay: ≥98.0% (HPLC)
• Optische Aktivität: [α]20/D +16±1°, c = 1% in ethyl acetate
• Eignung der Reaktion: reaction type: C-H Activation; reaction type: Fmoc solid-phase peptide synthesis; reagent type: ligand; reaction type: Peptide Synthesis
• Anwendung(en): peptide synthesis
• Funktionelle Gruppe: Fmoc; amine; carboxylic acid
• Lagertemp.: 2-8°C
• SMILES String: C[C@@H](OC(C)(C)C)[C@H](NC(=O)OCC1c2ccccc2-c3ccccc13)C(O)=O
• InChI: 1S/C23H27NO5/c1-14(29-23(2,3)4)20(21(25)26)24-22(27)28-13-19-17-11-7-5-9-15(17)16-10-6-8-12-18(16)19/h5-12,14,19-20H,13H2,1-4H3,(H,24,27)(H,25,26)/t14-,20+/m1/s1
• InChIKey: LZOLWEQBVPVDPR-VLIAUNLRSA-N

Beschreibung

Allgemeine Beschreibung

Fmoc-Thr(tBu)-OH also known as Fmoc-O-tert-butyl-L-threonine, is commonly used as amino acid building block in peptide synthesis.

Anwendung

Fmoc-Thr(tBu)-OH can be used to synthesize chlorofusin analogues via solid phase peptide synthesis. Additionally, it can serve as a protecting group for both the amine and the hydroxyl functions in solid-phase synthesis of complex depsipeptides.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)