444375

N-Benzoyl-(2R,3S)-3-phenylisoserin

98%

• Lineare Formel: C₆H₅CONHCH(C₆H₅)CH(OH)CO₂H
• CAS-Nummer: 132201-33-3
• Molekulargewicht: 285.29
• UNSPSC Code: 12352209
• eCl@ss: 32160406
• PubChem Substance ID: 24868119
• NACRES: NA.22
• MDL number: MFCD00274633

Eigenschaften

• Quality Segment: 100
• assay: 98%
• optical activity: [α]20/D −40°, c = 1.0 in ethanol
• reaction suitability: reaction type: solution phase peptide synthesis
• mp: 169-172 °C (lit.)
• application(s): peptide synthesis
• SMILES string: O[C@H]([C@@H](NC(=O)c1ccccc1)c2ccccc2)C(O)=O
• InChI: 1S/C16H15NO4/c18-14(16(20)21)13(11-7-3-1-4-8-11)17-15(19)12-9-5-2-6-10-12/h1-10,13-14,18H,(H,17,19)(H,20,21)/t13-,14+/m0/s1
• InChI key: HYJVYOWKYPNSTK-UONOGXRCSA-N

Beschreibung

Application

The presence of this chiral side chain has proven to be essential for the biological activity of taxol, one of the most promising anticancer agents being investigated. The challenging synthesis of taxol has stimulated interest in the attachment of the C-13 side chain to naturally derived taxanes like baccatin III.

Sicherheitshinweise

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves