412422

PAMAM-Dendrimer mit Ethylendiamin-Kern, Generation 3.0 -Lösung

20 wt. % in methanol

• Synonym(e): Starburst PAMAM-G 3
• Lineare Formel: [NH₂(CH₂)₂NH₂]:(G=3);dendri PAMAM(NH₂)₃₂
• CAS-Nummer: 153891-46-4
• Molekulargewicht: 6908.84
• MDL-Nummer: MFCD00197936
• UNSPSC-Code: 12162002
• NACRES: NA.23

Eigenschaften

• Beschreibung: amino surface groups
• Form: liquid
• Mol-Gew.: generation 3.0
• Leistungsmerkmale: core type ethylenediamine core (2-carbon core)
• Konzentration: 20 wt. % in methanol
• Anzahl Oberflächengruppen: 32
• Brechungsindex: n20/D 1.367
• bp: 64.7 °C
• Dichte: 0.863 g/mL at 25 °C
• Lagertemp.: 2-8°C

Beschreibung

Allgemeine Beschreibung

PAMAM dendrimer is a symmetrical polymer with a large number of terminal groups that can easily bind to biomolecules due to their biocompatibility and affinity. These dendrimers have a multivalent surface that contains envelopes and various active sites at the core with the attached dendrons. They are highly branched nanoscale polymers that are extensively used in the field of biomedicine for targeted drug delivery.[1]

Anwendung

PAMAM dendrimers can be used as transfection agents for the delivery of nucleic acids. For example, it can be used in the pulmonary delivery of siRNA directed against tumor necrosis factor (TNF).[2]

Physikalische Form

Contains 32 surface primary amino groups

Rechtliche Hinweise

Manufactured by Dendritech^®, Inc.

Dendritech is a registered trademark of Dendritech, Inc.

Sicherheitshinweise

• Piktogramme: GHS02,GHS06,GHS08
• Signalwort: Danger
• H-Sätze: H225,H301 + H311 + H331,H370
• P-Sätze: P210 - P233 - P280 - P301 + P310 - P303 + P361 + P353 - P304 + P340 + P311
• Gefahreneinstufungen: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• Zielorgane: Eyes,Central nervous system
• Lagerklassenschlüssel: 3 - Flammable liquids
• WGK: WGK 3
• Flammpunkt (°F): 51.8 °F - closed cup
• Flammpunkt (°C): 11 °C - closed cup