362824

Acetyltrimethylsilan

97%

• Synonym(e): 1-(Trimethylsilyl)-ethanon
• Lineare Formel: (CH₃)₃SiCOCH₃
• CAS-Nummer: 13411-48-8
• Molekulargewicht: 116.23
• Beilstein: 2071361
• MDL-Nummer: MFCD00134244
• UNSPSC-Code: 12352103
• PubChem Substanz-ID: 24862334
• NACRES: NA.22

Eigenschaften

• Assay: 97%
• Brechungsindex: n20/D 1.411 (lit.)
• Dichte: 0.811 g/mL at 25 °C (lit.)
• Lagertemp.: 2-8°C
• SMILES String: CC(=O)[Si](C)(C)C
• InChI: 1S/C5H12OSi/c1-5(6)7(2,3)4/h1-4H3
• InChIKey: REDWSDBFBCDPNI-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

Acetyltrimethylsilane is an organosilicon compound that is commonly used as a protective agent for alcohols and amines in organic synthesis. It is also used as a reagent in various reactions, which includes trimethylsilylation, condensation, carbon-carbon bond formation, and reductive amination reactions.

Anwendung

Acetyltrimethylsilane can be used as a reagent in the synthesis of dihydrophenanthrenes via a C-C insertion reaction. It is also used as a source of carbanion in the synthesis of unsymmetrical biaryls by carbanion-induced ring transformation of 2H-pyran-2-ones under mild basic conditions.

Sicherheitshinweise

• Piktogramme: GHS02,GHS07
• Signalwort: Danger
• H-Sätze: H225,H315,H319,H335
• P-Sätze: P210 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Irrit. 2 - Flam. Liq. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 3 - Flammable liquids
• WGK: WGK 3
• Flammpunkt (°F): 46.4 °F - closed cup
• Flammpunkt (°C): 8 °C - closed cup
• Persönliche Schutzausrüstung: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter