218944

Diethylstilbestrol, Mischung aus cis und trans

97%

• Synonym(e): DES
• Empirische Formel (Hill-System): C₁₈H₂₀O₂
• CAS-Nummer: 6898-97-1
• Molekulargewicht: 268.35
• NACRES: NA.22
• PubChem Substance ID: 24853100
• UNSPSC Code: 12352100
• EC Number: 200-278-5
• MDL number: MFCD00002373
• Assay: 97%

Eigenschaften

• assay: 97%
• mp: 170-172 °C (lit.)
• SMILES string: CC\C(c1ccc(O)cc1)=C(\CC)c2ccc(O)cc2
• InChI: 1S/C18H20O2/c1-3-17(13-5-9-15(19)10-6-13)18(4-2)14-7-11-16(20)12-8-14/h5-12,19-20H,3-4H2,1-2H3/b18-17+
• InChI key: RGLYKWWBQGJZGM-ISLYRVAYSA-N
• Gene Information: human ... ESR1(2099), ESR2(2100), ESRRG(2104) ; mouse ... Esr1(13982) ; rat ... Ar(24208), Esr1(24890)

Beschreibung

General description

Mechanisms of the isomerization processes of molecular and anionic diethylstilbestrol (DES) has been reported. Estrogen activity of cis- and trans-diethylstilbestrol has been evaluated. Diethylstilbestrol is a carcinogenic synthetic estrogen.

Application

Diethylstilbestrol was used as internal standard for the analysis of drug residues in urine of rats and calves by on-line HPLC with ultraviolet and continuous-flow fast atom bombardmentmass spectrometry detectors.

Sicherheitshinweise

• Piktogramme: GHS08,GHS07,GHS09
• Signalwort: Danger
• Gefahrencodes: H315,H319,H335,H350,H360FD,H410
• Sicherheitshinweise: P202 - P261 - P273 - P302 + P352 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1B - Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklasse: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Was ist los?: WGK 3
• PSA (Persönliche Schutzausrüstung): Eyeshields, Gloves, type P3 (EN 143) respirator cartridges