215430

N-tert.-Butyl-α-(4-pyridyl)-nitron-N′-oxid

99%

• Synonym(e): α-(4-Pyridyl N-oxid)-N-tert-Butylnitron, N-(4-Pyridylmethylen)-tert.-butylamin N,N′-dioxid, POBN
• Empirische Formel (Hill-System): C₁₀H₁₄N₂O₂
• CAS-Nummer: 66893-81-0
• Molekulargewicht: 194.23
• Beilstein: 1453764
• EG-Nummer: 266-512-3
• MDL-Nummer: MFCD00041022
• UNSPSC-Code: 12352100
• PubChem Substanz-ID: 24852894
• NACRES: NA.22

Eigenschaften

• Assay: 99%
• Form: solid
• mp (Schmelzpunkt): 183-185 °C (lit.)
• Löslichkeit: water: soluble 10 mg/mL, clear, colorless to faintly yellow
• SMILES String: CC(C)(C)\[N+]([O-])=C/c1cc[n+]([O-])cc1
• InChI: 1S/C10H14N2O2/c1-10(2,3)12(14)8-9-4-6-11(13)7-5-9/h4-8H,1-3H3/b12-8+
• InChIKey: RNRMWTCECDHNQU-XYOKQWHBSA-N

Beschreibung

Anwendung

Spin-trap suitable for detecting hydroxyl radicals and selenide radical anions.

Spin trap reagent used to measure ethanol oxidation to 1-hydroxyethyl radical (HER) which can bind to protein. Has also been used in studies of DNA methylation, iron-mediated polyunsaturated fatty acid peroxidation, and free-radical formation by Alzheimer β-amyloid peptide. The formation of hydroxyl radical in chondrocytes and cartilage has been detected using POBN.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)