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143057

Sigma-Aldrich

Aldrithiol™-4

98%

Synonym(e):

4,4′-Dipyridyl-disulfid, 4,4′-Dithiodipyridin

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1 G
€ 67,00
5 G
€ 198,00
25 G
€ 953,00

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1 G
€ 67,00
5 G
€ 198,00
25 G
€ 953,00

About This Item

Empirische Formel (Hill-System):
C10H8N2S2
CAS-Nummer:
2645-22-9
Molekulargewicht:
220.31
EG-Nummer:
220-158-6
MDL-Nummer:
MFCD00006423
UNSPSC-Code:
12352100
PubChem Substanz-ID:
24848571
NACRES:
NA.22

€ 67,00

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Qualitätsniveau

200

Assay

98%

Form

solid

mp (Schmelzpunkt)

76-78 °C (lit.)

Löslichkeit

95% ethanol: soluble 5%, clear, colorless to light yellow

Funktionelle Gruppe

disulfide

Lagertemp.

2-8°C

SMILES String

S(Sc1ccncc1)c2ccncc2

InChI

1S/C10H8N2S2/c1-5-11-6-2-9(1)13-14-10-3-7-12-8-4-10/h1-8H

InChIKey

UHBAPGWWRFVTFS-UHFFFAOYSA-N

Verwandte Kategorien

Anwendung

Thiol reagent.[1][2] Used to modify gold surfaces for protein studies.[3]

Rechtliche Hinweise

Aldrithiol is a trademark of Sigma-Aldrich Co. LLC

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

dust mask type N95 (US), Eyeshields, Gloves

Hier finden Sie alle aktuellen Versionen:

Analysenzertifikate (COA)

Lot/Batch Number
0000419160
0000419160
0000411738
0000411738
0000371406

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In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Shwu-Jiuan Sheu et al.
Investigative ophthalmology & visual science, 44(3), 1237-1244 (2003-02-26)
To identify the mechanisms by which oxidative stress with oxidizing agents alters the activity of ion channels in human retinal pigment epithelial (RPE) cells. The effects of oxidizing agents on ion currents were investigated in human RPE R-50 cells with
Nikitas Bistolas et al.
Biochemical and biophysical research communications, 314(3), 810-816 (2004-01-27)
The spectroelectrochemistry of camphor-bound cytochrome P450cam (P450cam) using gold electrodes is described. The electrodes were modified with either 4,4(')-dithiodipyridin or sodium dithionite. Electrolysis of P450cam was carried out when the enzyme was in solution, while at the same time UV-visible
Hong Xie et al.
Biophysical journal, 91(8), 2882-2891 (2006-08-01)
To understand better the modulation of ryanodine receptors (RyRs) during oxidative stress, the effect of 4,4'-dithiodipyridine (DTDP), a cell-permeant and thiol-reactive oxidant, on global Ca(2+) signal and spontaneous Ca(2+) sparks of rat ventricular myocytes was investigated. It was shown that
Rosa E Hansen et al.
Analytical biochemistry, 363(1), 77-82 (2007-02-09)
Experimental determination of the number of thiols in a protein requires methodology that combines high sensitivity and reproducibility with low intrinsic thiol oxidation disposition. In detection of disulfide bonds, it is also necessary to efficiently reduce disulfides and to quantify
F Peter Guengerich et al.
Biochemistry, 42(37), 10965-10970 (2003-09-17)
The active site cysteine of human O(6)-alkylguanine-DNA alkyltransferase (hAGT), Cys145, was shown to be highly reactive with model electrophiles unrelated to substrates, including 1-chloro-2,4-dinitrobenzene. The high reactivity suggested that the Cys145 thiolate anion might be stable at neutral pH. The
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Questions

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  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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