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Merck

ADORA1

adenosine A1 receptor

Sinónimos:
RDC7
Especie:
ID UniProtKB:
ID del gen:
  • Human(134) Summary: The protein encoded by this gene is an adenosine receptor that belongs to the G-protein coupled receptor 1 family. There are 3 types of adenosine receptors, each with a specific pattern of ligand binding and tissue distribution, and together they regulate a diverse set of physiologic functions. The type A1 receptors inhibit adenylyl cyclase, and play a role in the fertilization process. Animal studies also suggest a role for A1 receptors in kidney function and ethanol intoxication. Transcript variants with alternative splicing in the 5' UTR have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(11539) adenosine A1 receptor
  • Rat(29290) adenosine A1 receptor
  • chicken(374212) adenosine A1 receptor
  • sheep(101109816) adenosine A1 receptor
  • cow(282133) adenosine A1 receptor
  • domestic guinea pig(100135472) adenosine A1 receptor
  • naked mole-rat(101704638) adenosine A1 receptor
  • Zebrafish(100150997) adenosine A1 receptor
  • dog(403961) adenosine A1 receptor
  • domestic cat(101100536) adenosine A1 receptor

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Small Molecule - Agonist

Referencia del producto
Descripción
Especie
(−)-N6-(2-Phenylisopropyl)adenosine, solid,
Especie
human
Adenosine, ,
Especie
human
Formycin A, from Streptomyces kaniharaensis, ≥98% (HPLC),
Especie
human
Adenosine, United States Pharmacopeia (USP) Reference Standard,
Especie
human
Adenosine, Pharmaceutical Secondary Standard; Certified Reference Material,
Especie
human

Small Molecule - Antagonist

Referencia del producto
Descripción
Especie
Cordycepin, from Cordyceps militaris,
Especie
rat
Tubercidin, from Streptomyces tubercidicus, ~95%,
Especie
rat
8-Cyclopentyl-1,3-dimethylxanthine, ≥98% (HPLC), powder,
Especie
human
3-Isobutil-1-metilxantina, ≥99%, BioUltra,
Especie
rat
Hematoxylin, ,
Especie
rat

Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-Adenosine A1 Receptor Antibody, Chemicon®, from rabbit,
Reactividad de especies
guinea pig, human, pig, rat, sheep
Aplicación
ELISA
immunocytochemistry

immunohistochemistry

western blot
Anti-ADORA1 antibody produced in rabbit, ,
Reactividad de especies
human, mouse
Aplicación
immunohistochemistry
western blot

Small Molecule - Blocker

Referencia del producto
Descripción
Especie
Nitrendipine, >95%, powder,
Especie
human, rat
Caffeine, anhydrous, 99%, FCC, FG,
Especie
mouse, human, rat
Caffeine, Sigma Reference Standard, vial of 250 mg,
Especie
mouse, human, rat
Caffeine, anhydrous, tested according to Ph. Eur.,
Especie
mouse, human, rat
Caffeine, meets USP testing specifications, anhydrous,
Especie
mouse, human, rat

Small Molecule - Inhibitor

Referencia del producto
Descripción
Especie
EHNA hydrochloride, ≥98% (HPLC),
Especie
human
Dilazep dihydrochloride, powder,
Especie
human
8-(3-Chlorostyryl)caffeine, ≥98% (HPLC), solid,
Especie
human, rat, mouse
5′-Deoxy-5′-(methylthio)adenosine, ,
Especie
human, rat, mouse
α-Naphthoflavone, ≥98%,
Especie
human, rat

Small Molecule - Ligand

Referencia del producto
Descripción
Especie
2-Chloro-2′-deoxyadenosine, antileukemic,
Especie
rat, human
1,7-Dimethylxanthine, ~98%, solid,
Especie
rat, human
Chloro-IB-MECA, solid, ≥98% (HPLC),
Especie
human, rat
Adenosine, ≥99%,
Especie
human, rat
Theophylline, anhydrous, ≥99%, powder,
Especie
mouse, human, rat

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting mouse Adora1,
Especie
mouse
MISSION® esiRNA, targeting human ADORA1,
Especie
human