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Chlormethiazole hydrochloride

Name: Chlormethiazole hydrochloride
Brand: SIGMA
Price: 133.45 USD
Availability: InStock

≥98% (HPLC), GABAA agonist, powder

Synonym(s):

4-methyl-5-(β-chloroethyl)thiazole hydrochloride, 5-(2-Chloroethyl)-4-methylthiazole hydrochloride, Clomethiazole hydrochloride, Somnevrin hydrochloride

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Pack Size	SKU	Availability	Price
10 mg		Available to ship TODAYfromMILWAUKEE	$157.00 $133.45
50 mg		Available to ship TODAYfromMILWAUKEE	$561.00 $476.85

About This Item

Empirical Formula (Hill Notation):

C₆H₈ClNS · HCl

CAS Number:

6001-74-7

Molecular Weight:

198.11

UNSPSC Code:

12352200

PubChem Substance ID:

329774745

NACRES:

NA.77

MDL number:

MFCD00673948

Assay:

≥98% (HPLC)

Form:

powder

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Properties

Product Name

Chlormethiazole hydrochloride, ≥98% (HPLC), powder

description

Store desiccated

Quality Segment

100

assay

≥98% (HPLC)

form

powder

color

off-white

solubility

H₂O: soluble >10 mg/mL

originator

AstraZeneca

SMILES string

Cl.Cc1ncsc1CCCl

InChI

1S/C6H8ClNS.ClH/c1-5-6(2-3-7)9-4-8-5;/h4H,2-3H2,1H3;1H

InChI key

OFXYKSLKNMTBHK-UHFFFAOYSA-N

Description

Biochem/physiol Actions

GABA_A agonist; glycine receptor modulator.

Chlormethiazole serves as an anticonvulsant. It is useful in treating alcohol addiction and eclampsia. Chlormethiazole is also useful in treating convulsive status epilepticus. Long term administration of chlormethiazole leads to addiction to the drug.

Features and Benefits

This compound is a featured product for ADME Tox and Neuroscience research. Discover more featured ADME Tox and Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound was developed by AstraZeneca. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

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This Item	B019	SML2803	C8417
Sigma-Aldrich C1240 Chlormethiazole hydrochloride	Sigma-Aldrich B019 Phenoxybenzamine hydrochloride	Sigma-Aldrich SML2803 Tebanicline hydrochloride	Sigma-Aldrich C8417 N-(2-Chloroethyl)-N-ethyl-2-bromobenzylamine hydrochloride
form powder	form powder	form powder	form solid
assay ≥98% (HPLC)	assay ≥97%	assay ≥98% (HPLC)	assay ≥98%
Quality Level 100	Quality Level 100	Quality Level 100	Quality Level 200
solubility H₂O: soluble >10 mg/mL	solubility H₂O: slightly soluble, alcohol: soluble, propylene glycol: soluble	solubility H₂O: 2 mg/mL, clear	solubility H₂O: 48 mg/mL, 0.1 M NaOH: 7 mg/mL, ethanol: soluble
color off-white	color white	color white to beige	color white
originator AstraZeneca	originator Wellspring	originator -	originator -