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Phenoxybenzamine hydrochloride

Name: Phenoxybenzamine hydrochloride
Brand: SIGMA
Price: 137 USD
Availability: InStock

≥97%, powder

Synonym(s):

N-(2-Chloroethyl)-N-(1-methyl-2-phenoxyethyl)benzylamine hydrochloride

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Pack Size	SKU	Availability	Price
250 mg		Available to ship onMay 13, 2026fromMILWAUKEE	$137.00

About This Item

Empirical Formula (Hill Notation):

C₁₈H₂₂ClNO · HCl

CAS Number:

63-92-3

Molecular Weight:

340.29

NACRES:

NA.77

PubChem Substance ID:

24277760

UNSPSC Code:

12352116

EC Number:

200-569-7

MDL number:

MFCD00055152

Assay:

≥97%

Form:

powder

Quality level:

100

$137.00

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Properties

Quality Level

100

assay

≥97%

form

powder

color

white

solubility

H₂O: slightly soluble, alcohol: soluble, propylene glycol: soluble

originator

Wellspring

storage temp.

2-8°C

SMILES string

Cl[H].CC(COc1ccccc1)N(CCCl)Cc2ccccc2

InChI

1S/C18H22ClNO.ClH/c1-16(15-21-18-10-6-3-7-11-18)20(13-12-19)14-17-8-4-2-5-9-17;/h2-11,16H,12-15H2,1H3;1H

InChI key

VBCPVIWPDJVHAN-UHFFFAOYSA-N

Gene Information

human ... ADRA1A(148), ADRA1B(147), ADRA1D(146), ADRA2A(150), ADRA2B(151), ADRA2C(152)

Description

Biochem/physiol Actions

Calmodulin antagonist; α-adrenoceptor antagonist.

Features and Benefits

This compound is a featured product for ADME Tox research. Click here to discover more featured ADME Tox products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound was developed by Wellspring. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

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Show Differences

1 of 1

This Item	SML0667	C8417	SML0036
Sigma-Aldrich B019 Phenoxybenzamine hydrochloride	Sigma-Aldrich SML0667 PF-429242 dihydrochloride	Sigma-Aldrich C8417 N-(2-Chloroethyl)-N-ethyl-2-bromobenzylamine hydrochloride	Sigma-Aldrich SML0036 Procarbazine hydrochloride
form powder	form powder	form solid	form powder
assay ≥97%	assay ≥98% (HPLC)	assay ≥98%	assay ≥98% (HPLC)
Quality Level 100	Quality Level 100	Quality Level 200	Quality Level 100
storage temp. 2-8°C	storage temp. 2-8°C	storage temp. -	storage temp. 2-8°C
solubility H₂O: slightly soluble, propylene glycol: soluble, alcohol: soluble	solubility H₂O: 15 mg/mL, clear	solubility H₂O: 48 mg/mL, 0.1 M NaOH: 7 mg/mL, ethanol: soluble	solubility DMSO: ≥18 mg/mL
color white	color white to beige	color white	color white to tan

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pictograms

GHS08,GHS07

signalword

Warning

hcodes

H302,H351

pcodes

P201 - P301 + P312 + P330 - P308 + P313

Hazard Classifications

Acute Tox. 4 Oral - Carc. 2

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges

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Articles

Discover Bioactive Small Molecules for ADME/Tox

Is dexmedetomidine the agent of choice in the resection of pheochromocytoma?

Harsha V Polavarapu et al.

The American surgeon, 78(3), E127-E128 (2012-04-25)

Selective α1-adrenoceptor antagonist (controlled release tablets) in preoperative management of pheochromocytoma.

Yu Zhu et al.

Endocrine, 38(2), 254-259 (2010-11-04)

The objective of this article is to evaluate the efficacy of Doxazosin Mesylate Controlled Release Tablets for preoperative treatment of patients with pheochromocytoma. Between 2003 and 2008, 67 patients with confirmed diagnoses of pheochromocytoma were enrolled in this study. According

Pheochromocytoma crisis is not a surgical emergency.

Anouk Scholten et al.

The Journal of clinical endocrinology and metabolism, 98(2), 581-591 (2013-01-04)

Pheochromocytoma crisis is a feared and potentially lethal complication of pheochromocytoma. We sought to determine the best treatment strategy for pheochromocytoma crisis patients and hypothesized that emergency resection is not indicated. Retrospective cohort study (1993-2011); literature review (1944-2011). Tertiary referral

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Global Trade Item Number

SKU	GTIN
B019-250MG	04061833419571

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