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Molecular Biology & Functional Genomics

Nucleic Acid Electrophoresis, Transfer, and Quantitation

Molecular biology and functional genomic reagents and resources enable scientists to research the molecular machinery and pathways that drive all biological systems. From gene editing, DNA and RNA, oligos, qPCR, to protein expression, detection, and quantification, our comprehensive offering of world-class reagents are readily available for you to make discoveries in both healthy and disease tissues. Developed by our team of experts, explore our rich technical content, troubleshooting guides, and protocols and drive your research forward. 

DNA and RNA cleanup purification kits

Nucleic Acid Purification

DNA and RNA extraction, purification, and reaction clean-up reagents and kits.

PCR & Amplification

PCR reagents, kits, whole genome amplification, PCR consumables, and thermocyclers for your PCR workflow needs.

PCR & Amplification

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Oligos & qPCR Probes
Oligos & qPCR Probes

Meet your research needs with custom products from our comprehensive portfolio of DNA and RNA oligos, qPCR probes and peptides.

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NGS Library Preparation
NGS Library Preparation

Prepare your library for next-gen sequencing. Isolate, fragment, repair, and link nucleic acids with adapters using ligation or tagmentation methods. Essential step before DNA/RNA sequencing.

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Gene Editing & Functional Genomics
Gene Editing & Functional Genomics

Sigma-Aldrich® Advanced Genomics provides cutting-edge gene editing and modulation technologies, including CRISPR, Cas9, and RNAi.

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Epigenetics
Epigenetics

Epigenetic reagents and resources for investigating RNA species, DNA methylation, chromatin modifications, and histone modifications.

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Microbiome
Microbiome

Comprehensive Gut Microbiome Analysis: Uncover a holistic solution encompassing sample prep, sequencing, bioinformatics, and statistics. From 16S to WGS.

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Cloning & Expression
Cloning & Expression

Explore our comprehensive offering of restriction enzymes, protein expression vectors, transfection reagents and protein expression technologies for your molecular cloning and protein expression workflow needs.

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Nucleic Acid Electrophoresis & Hybridization
Nucleic Acid Electrophoresis & Hybridization

Genomic analysis tools for DNA and RNA detection and quantitation, including nucleic acid stains, sample loading buffers, precast agarose gels, transfer membranes, as well as biotin, fluorescein, and DIG RNA and DNA labeling reagents.

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Roche Life Science Products
Roche Life Science Products

Roche Life Science Products provide dependable reagents for breakthrough research, ensuring high-quality, reproducible results.

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cell lines (2499)

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peptides (207)

albumins (157)

human (1982)

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Mouse x Mouse Hybridoma (307)

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rat (195)

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cell culture | mammalian (3549)

cell culture | plant (162)

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cell culture | stem cell (100)

ELISA (67)

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Dimethyl sulfoxide
D2650

Dimethyl sulfoxide

Hybri-Max, sterile-filtered, BioReagent, suitable for hybridoma, ≥99.7%

Dulbecco′s Phosphate Buffered Saline
D8537

Dulbecco′s Phosphate Buffered Saline

liquid, Modified, without calcium chloride and magnesium chloride, liquid, sterile-filtered, suitable for cell culture

Laminin from Engelbreth-Holm-Swarm murine sarcoma basement membrane
L2020

Mouse Laminin

from Engelbreth-Holm-Swarm murine sarcoma basement membrane, 0.2 μm filtered, liquid, 1-2 mg/mL, suitable for cell culture

Dimethyl sulfoxide
D2438

Dimethyl sulfoxide

sterile-filtered, BioPerformance Certified, meets EP, USP testing specifications, suitable for hybridoma

RPMI-1640 Medium
R8758

RPMI-1640 Medium

With ʟ-glutamine, sodium bicarbonate, liquid, sterile-filtered, suitable for cell culture

Bovine Serum Albumin
A7030

Bovine Serum Albumin

heat shock fraction, protease free, fatty acid free, essentially globulin free, pH 7, ≥98%

Dulbecco′s Modified Eagle′s Medium - high glucose
D6429

DMEM - high glucose

With sodium bicarbonate, ʟ-glutamine and sodium pyruvate, liquid, sterile-filtered, suitable for cell culture

Insulin solution human
I9278

Insulin solution human

sterile-filtered, BioXtra, suitable for cell culture

Dulbecco′s Modified Eagle′s Medium - high glucose
D5796

DMEM - high glucose

With sodium Bicarbonate and ʟ-glutamine, without sodium pyruvate, liquid, sterile-filtered, suitable for cell culture

Millipore<SUP>®</SUP> Steriflip<SUP>®</SUP> Vacuum Tube Top Filter
SCGP00525

Millipore® Steriflip® Vacuum Tube Top Filter

pore size 0.22 μm, polyethersulfone membrane, funnel capacity 50 mL, pack of 25 ea

Dimethyl sulfoxide
D2653

Dimethyl sulfoxide

Hybri-Max, 0.2 μm filtered, BioReagent, suitable for hybridoma, ≥99.7%, Ampoule

Bovine Serum Albumin
A9647

Bovine Serum Albumin

heat shock fraction, pH 7, ≥98%

Millipore<SUP>®</SUP> Stericup<SUP>®</SUP> Quick Release Vacuum Filtration System
S2GPU05RE

Millipore® Stericup® Quick Release Vacuum Filtration System

pore size 0.22 μm, polyethersulfone membrane, filter capacity 500 mL, pack of 12 ea

Fetal Bovine Serum
F4135

Fetal Bovine Serum

USA origin, Heat Inactivated, sterile-filtered, suitable for cell culture, suitable for insect cell culture, suitable for hybridoma

Human Serum
H4522

Human Serum

from human male AB plasma, USA origin, sterile-filtered

Trypsin-EDTA solution
T4049

Trypsin-EDTA solution

0.25%, sterile-filtered, BioReagent, suitable for cell culture, 2.5 g porcine trypsin and 0.2 g EDTA, 4Na per liter of Hanks′ Balanced Salt Solution with phenol red

Fetal Bovine Serum
F2442

Fetal Bovine Serum

USA origin, sterile-filtered, suitable for cell culture, suitable for hybridoma

Poly-<SC>L</SC>-lysine solution
P4707

Poly-ʟ-Lysine Hydrobromide

synthetic, liquid, 0.01%, suitable for cell culture

Accutase<SUP>®</SUP> solution
A6964

Accutase® solution

sterile-filtered, suitable for cell culture

Poly-<SC>L</SC>-ornithine solution
P4957

Poly-ʟ-Ornithine

synthetic, mol wt 30,000-70,000, liquid, 0.01%, suitable for cell culture

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