Skip to Content
MilliporeSigma
HomeProductsChemistry & BiochemicalsCatalystsOlefin Metathesis

Olefin Metathesis

Slide 1 of 3
Ring-opening metathesis is driven by the is driven by the force to relieve ring strain. In absence of excess of a second reaction partner, polymerization occurs (ROMP).
Cross metathesis brings two olefins together in an intermolecular reaction to give an olefin product bearing substituent from each of the starting olefins.
Ring-closing metathesis is an intramolecular reaction of an acyclic diene to form a ring.

We are committed to helping you reach new frontiers through an ever-expanding, always innovative portfolio of products for olefin metathesis. In line with this goal, we have partnered with Umicore PMC to bring you an outstanding range of olefin metathesis catalysts for chemical synthesis. Our exclusive collaboration not only gives you direct access to Umicore’s Grubbs Catalyst® technology, but also their development expertise. You’ll enjoy rapid, reliable supply of milligram to multi-kilogram volumes, at the best value, with Umicore license rights included. Moreover, you’ll benefit from dedicated technical guidance, supported by Nobel Laureate Robert Grubbs.

Related Product Resources

Olefin Metathesis Reaction Planning and Troubleshooting
Ruthenium Catalysts Overview

Selected Best Metathesis Practices

  • Consider Concentration: Run cross-metathesis reactions concentrated and macrocyclization reactions diluted.
  • Oust Oxygen: Degassing reactions with an inert gas prior to adding a Grubbs catalyst can improve catalyst lifetime and efficiency. Degassing during the reaction has the added benefit of efficiently removing ethylene from metathesis reactions where it is generated.
  • Solvent Selection: Consider solubility and use non-coordinating solvents when possible, such as cyclohexane, toluene, or dichloromethane.
  • For more suggestions on metathesis reaction planning and troubleshooting, view the Metathesis Application Guide

Easy Access to Grubbs Catalyst® Technology

Enjoy unparalleled access to Grubbs Catalyst® technology and experience the many benefits of our exclusive partnership.

  • Secure supply chain of metathesis catalysts from milligram to multi-kilogram volumes
  • Rapid delivery of R&D quantities
  • Access to technical expertise, supported by Nobel Laureate Robert Grubbs
  • Umicore license rights included in listed product price
Related Product Categories
Transition Metal Catalysts
Discover our unparalleled portfolio of transition metal catalysts for your different organic and organometallic chemistry-based applications.
Related Applications
Metathesis
Olefin metathesis involves an organic reaction that redistributes fragments of alkenes (olefins) by cleavage and transformation of carbon-carbon double bonds.
RELATED SERVICES
Bulk Quotation Request
Use this form to request price and delivery information on critical raw materials in your supply chain, unique and large package sizes or bulk quantities that are not available on the site and any other customization requests
SYNTHIA™ Retrosynthesis Software
Our custom cell culture product design experts can offer advice and support as you scale your bioprocess from clinical to commercial supply, assisting with liquid products, dry powder products, selection of raw materials, quality testing, flexible product packaging, and product documentation.
Small Molecule Library Design (Aldrich Market Select)
Streamline the management of your screening compounds with our Aldrich Market Select online order center for small molecule libraries, comprising over 14 million chemistry building blocks and other useful services.

Highlights

Aldrichimica Acta review on second-generation metathesis catalysts

Aldrichimica Acta review on ROM polymerization in facilitated synthesis

Aldrichimica Acta review on CM of nitrogen-containing systems

Sign In To Continue

To continue reading please sign in or create an account.

Don't Have An Account?