B3563

Bifonazole

≥98% (HPLC)

• Synonym(s): 1-(p,α-Diphenylbenzyl)imidazole
• Empirical Formula (Hill Notation): C₂₂H₁₈N₂
• CAS Number: 60628-96-8
• Molecular Weight: 310.39
• NACRES: NA.77
• PubChem Substance ID: 329773219
• UNSPSC Code: 12352200
• EC Number: 262-336-6
• MDL number: MFCD00865567
• Assay: ≥98% (HPLC)
• Form: powder

Properties

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to off-white
• solubility: DMSO: >10 mg/mL
• originator: Bayer
• storage temp.: room temp
• SMILES string: c1ccc(cc1)C(c2ccc(cc2)-c3ccccc3)n4ccnc4
• InChI: 1S/C22H18N2/c1-3-7-18(8-4-1)19-11-13-21(14-12-19)22(24-16-15-23-17-24)20-9-5-2-6-10-20/h1-17,22H
• InChI key: OCAPBUJLXMYKEJ-UHFFFAOYSA-N

Description

Biochem/physiol Actions

Bifonazole is an imidazole-based anti-fungal agent with broad spectrum activity against many fungi, molds, yeast and some Gram-positive bacteria. Bifonazole inhibits ergosterol biosynthetic protein 28 and Cytochrome P450 2B4.

Bifonazole is used to treat several infections such as onychomycoses, otomycoses, erythrasma, psoriasis, sebopsoriasis, seborrhoeic dermatitis and rosacea.[1] Bifonazole is also used as an important drug to treat melanoma.

Features and Benefits

This compound was developed by Bayer. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H302
• pcodes: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class: 11 - Combustible Solids
• wgk: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable