1.06574

di-Sodium hydrogen phosphate heptahydrate

EMPROVE^® ESSENTIAL, DAC, USP

• Synonym(s): Sodium phosphate dibasic heptahydrate, Disodium hydrogen phosphate heptahydrate, Disodium phosphate
• Linear Formula: Na₂HPO₄ · 7H₂O
• CAS Number: 7782-85-6
• Molecular Weight: 268.07
• MDL number: MFCD00149180
• UNSPSC Code: 12352302
• EC Index Number: 231-448-7

Properties

• agency: DAC; USP
• Quality Level: 500
• vapor density: 4.9 (vs air)
• product line: EMPROVE^® ESSENTIAL
• form: solid
• pH: 8.7-9.3 (25 °C, 50 g/L in H₂O)
• mp: 48 °C (Elimination of water of crystallisation)
• solubility: 154 g/L
• density: 1.68 g/mL at 25 °C (lit.)
• application(s): liquid formulation; ophthalmics; pharmaceutical; semi-solid formulation; solid formulation
• storage temp.: 2-30°C
• SMILES string: O.O.O.O.O.O.O.[Na+].[Na+].OP([O-])([O-])=O
• InChI: 1S/2Na.H3O4P.7H2O/c;;1-5(2,3)4;;;;;;;/h;;(H3,1,2,3,4);7*1H2/q2*+1;;;;;;;;/p-2
• InChI key: PYLIXCKOHOHGKQ-UHFFFAOYSA-L

Description

General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

di-Sodium hydrogen phosphate heptahydrate is typically used as a phosphate buffer system component for biomolecule downstream chromatography steps or final liquid formulation.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class: 13 - Non Combustible Solids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable