1.37039

Potassium dihydrogen phosphate

crystalline, EMPROVE^® EXPERT, Ph. Eur., BP, JPC, NF

• Synonym(s): Potassium phosphate monobasic, mono-Potassium orthophosphate, Potassium biphosphate, Potassium phosphate monobasic, Monopotassium phosphate, Potassium dihydrogen phosphate, prim.-Potassium phosphate
• Linear Formula: KH₂PO₄
• CAS Number: 7778-77-0
• Molecular Weight: 136.09
• MDL number: MFCD00011401
• UNSPSC Code: 12352302
• EC Index Number: 231-913-4

Properties

• agency: BP; JPC; NF; Ph. Eur.
• Quality Level: 500
• product line: EMPROVE^® EXPERT
• assay: ≥99.0% dry basis (alkalimetric); 98.0-100.5% (alkalimetric)
• form: crystalline; solid
• feature: RNase and DNase free
• pH: 4.2-4.6 (20 °C, 20 g/L in H₂O)
• mp: 252.6 °C (lit.)
• density: 2.338 g/mL at 25 °C (lit.)
• application(s): liquid formulation; parenterals; pharma/biopharma processes; pharmaceutical
• storage temp.: 2-30°C
• SMILES string: [K+].OP(O)([O-])=O
• InChI: 1S/K.H3O4P/c;1-5(2,3)4/h;(H3,1,2,3,4)/q+1;/p-1
• InChI key: GNSKLFRGEWLPPA-UHFFFAOYSA-M

Description

General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Potassium dihydrogen phosphate is typically used as a phosphate buffer system component for biomolecule downstream chromatography steps or final liquid formulation.
Due to its low microbial and endotoxin limits, Potassium dihydrogen phosphate Emprove^® Expert is especially suitable for high-risk applications.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class: 13 - Non Combustible Solids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable