1.06585

di-Sodium hydrogen phosphate

anhydrous, EMPROVE^® ESSENTIAL, Ph. Eur., BP, JPE, USP, E 339

• Synonym(s): Sodium phosphate dibasic, sec-Sodium phosphate, Disodium hydrogen phosphate, Disodium phosphate, Sodium hydrogenphosphate
• Linear Formula: Na₂HPO₄
• CAS Number: 7558-79-4
• Molecular Weight: 141.96
• MDL number: MFCD00003496
• UNSPSC Code: 12352302
• E Number: E339
• EC Index Number: 231-448-7

Properties

• agency: BP; JPE; Ph. Eur.; USP
• Quality Level: 500
• product line: EMPROVE^® ESSENTIAL
• form: solid
• pH: 8.7-9.3 (20 °C, 10 g/L in H₂O)
• pKa (25 °C): (1) 2.15, (2) 6.82, (3) 12.38 (phosphoric acid)
• mp: 250 °C (decomposition)
• application(s): liquid formulation; ophthalmics; pharmaceutical; semi-solid formulation; solid formulation
• storage temp.: 2-30°C
• SMILES string: [Na+].[Na+].[H]OP([O-])([O-])=O
• InChI: 1S/2Na.H3O4P/c;;1-5(2,3)4/h;;(H3,1,2,3,4)/q2*+1;/p-2
• InChI key: BNIILDVGGAEEIG-UHFFFAOYSA-L

Description

General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

di-Sodium hydrogen phosphate anhydrous is typically used as a phosphate buffer system component for biomolecule downstream chromatography steps or final liquid formulation.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class: 13 - Non Combustible Solids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable