1.06048

Dichloromethane

for spectroscopy Uvasol^®

• Synonym(s): DCM, Methylene chloride, Methylene dichloride, Methylene chloride
• Empirical Formula (Hill Notation): CH₂Cl₂
• CAS Number: 75-09-2
• Molecular Weight: 84.93
• Beilstein/REAXYS Number: 1730800
• MDL number: MFCD00000881
• UNSPSC Code: 12191502
• EC Index Number: 200-838-9
• NACRES: NA.03

Properties

• vapor density: 2.9 (vs air)
• Quality Level: 100
• vapor pressure: 24.45 psi ( 55 °C); 6.83 psi ( 20 °C)
• assay: ≥99.9% (GC)
• form: liquid
• autoignition temp.: 1223 °F; 605 °C (DIN 51794)
• potency: 1600 mg/kg LD₅₀, oral (Rat); >2000 mg/kg LD₅₀, skin (Rat)
• contains: ~50 ppm 2-methyl-2-butene as stabilizer
• expl. lim.: 22 %
• technique(s): UV/Vis spectroscopy: suitable
• impurities: ≤0.0002 meq/g Acidity; ≤0.0002 meq/g Alkalinity; ≤0.01% Water
• evapn. residue: ≤0.0002%
• color: APHA: ≤10
• transmittance: 235 nm, ≥30%; 240 nm, ≥70%; 245 nm, ≥85%; 250 nm, ≥95%; 255 nm, ≥98%
• refractive index: n20/D 1.424 (lit.)
• pH: 7 (20 °C)
• bp: 39.8-40 °C (lit.)
• mp: -95 °C; −95 °C (lit.)
• density: 1.325 g/mL at 25 °C (lit.)
• UV absorption: λ: 235 nm A_max: ≤0.52; λ: 240 nm A_max: ≤0.16; λ: 245 nm A_max: ≤0.07; λ: 250 nm A_max: ≤0.02; λ: 255 nm A_max: ≤0.01
• storage temp.: 2-30°C
• SMILES string: ClCCl
• InChI: 1S/CH2Cl2/c2-1-3/h1H2
• InChI key: YMWUJEATGCHHMB-UHFFFAOYSA-N

Description

General description

Accurate analytic results in UV/VIS and infrared spectroscopy depend on the use of very pure solvents for sample preparation. The Uvasol<TMSYMBOL></TMSYMBOL> solvents range has been specially designed for spectroscopy and other applications requiring solvents of the highest spectral purity. The refinement process allows a greater degree of security in applications and avoids misinterpretation of analytical results caused by traces of UV, IR and fluorescence contamination. Uvasol<TMSYMBOL></TMSYMBOL> solvents offer best UV transmittance. In all specifications the minimum transmittance for 5 typical wavelengths are identified.

Application

• Intra-Species Variations of Bioactive Compounds of Two Dictyota Species from the Adriatic Sea: Antioxidant, Antimicrobial, Dermatological, Dietary, and Neuroprotective Potential.: This study analyzes the bioactive compounds of Dictyota species, detailing their potential uses in various therapeutic areas. It highlights dichloromethane′s role in extracting these compounds, enhancing their analytical characterization and understanding their effects (Martić et al., 2023).



• Production of Two Isomers of Sphaeralcic Acid in Hairy Roots from Sphaeralcea angustifolia.: This research focuses on the production of sphaeralcic acid isomers in hairy root cultures, with a significant mention of dichloromethane used in the extraction processes. The study aids in understanding the compound′s stability and bioactivity, crucial for developing pharmaceutical applications (Barrera et al., 2023).



• Chemical Defense against Herbivory in the Brown Marine Macroalga Padina gymnospora Could Be Attributed to a New Hydrocarbon Compound.: Investigates the chemical defenses of Padina gymnospora against herbivores, with a focus on a new hydrocarbon compound isolated using dichloromethane. This research underscores the importance of solvent choice in the extraction and characterization of marine natural products (Pereira et al., 2023).



• Isolation and Characterization of One New Natural Compound with Other Potential Bioactive Secondary Metabolites from Glycosmis cyanocarpa (Blume) Spreng. (Family: Rutaceae).: Details the isolation of new natural compounds from Glycosmis cyanocarpa, emphasizing the role of dichloromethane in the extraction process. This article provides insights into the potential pharmacological applications of these compounds (Islam et al., 2023).



• Scutellaria petiolata Hemsl. ex Lace & Prain (Lamiaceae).: A New Insight in Biomedical Therapies.: Discusses the biomedical potential of Scutellaria petiolata, highlighting the use of dichloromethane in the extraction of bioactive compounds. This study contributes to the understanding of the therapeutic applications of the plant′s extracts (Mubin et al., 2022).

Analysis Note

Evaporation Number: 1.9

Purity (GC): ≥ 99.9 %
Evaporation residue: ≤ 0.0002 %
Water: ≤ 0.01 %
Color: ≤ 10 Hazen
Acidity: ≤ 0.0002 meq/g
Alkalinity: ≤ 0.0002 meq/g
Fluorescence (as quinine at 254 nm): ≤ 1.0 ppb
Fluorescence (as quinine at 365 nm): ≤ 1.0 ppb
Transmission (at 235 nm): ≥ 30 %
Transmission (at 240 nm): ≥ 70 %
Transmission (at 245 nm): ≥ 85 %
Transmission (at 250 nm): ≥ 95 %
Transmission (from 255 nm): ≥ 98 %
Absorbance (at 235 nm): ≤ 0.52
Absorbance (at 240 nm): ≤ 0.16
Absorbance (at 245 nm): ≤ 0.07
Absorbance (at 250 nm): ≤ 0.02
Absorbance (from 255 nm): ≤ 0.01
The product is stabilized with about 50 ppm 2-Methyl-2-butene
Meet the requirements of "Specific use spectroscopy" according ACS

Other Notes

Explore various lab safety accessories and equipment for safe handling of solvents to increase your safety level from the first usage.

Legal Information

UVASOL is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• pictograms: GHS07,GHS08
• signalword: Warning
• hcodes: H315 - H319 - H336 - H351
• pcodes: P202 - P261 - P264 - P302 + P352 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Carc. 2 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Central nervous system
• Storage Class: 6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• wgk_germany: WGK 2
• flash_point_f: does not flash
• flash_point_c: does not flash