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650463

Sigma-Aldrich

Dichloromethane

HPLC Plus, for HPLC, GC, and residue analysis, ≥99.9%, contains 50-150 ppm amylene as stabilizer

Synonym(s):

methylene chloride, Methylene chloride

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About This Item

Empirical Formula (Hill Notation):
CH2Cl2
CAS Number:
Molecular Weight:
84.93
Beilstein/REAXYS Number:
1730800
EC Number:
MDL number:
UNSPSC Code:
12190000
PubChem Substance ID:
NACRES:
NA.04

grade

HPLC Plus
for residue analysis

Quality Level

vapor density

2.9 (vs air)

vapor pressure

24.45 psi ( 55 °C)
6.83 psi ( 20 °C)

assay

≥99.9%

form

liquid

autoignition temp.

1223 °F

contains

50-150 ppm amylene as stabilizer

expl. lim.

22 %

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

impurities

≤ 1.0 ppb Fluorescence (quinine) at 365 nm
≤0.01% water

evapn. residue

≤0.0001%

halogenated residue

≤10 ng/L (as heptachlor epoxide)

refractive index

n20/D 1.424 (lit.)

bp

39.8-40 °C (lit.)

mp

−95 °C (lit.)

density

1.325 g/mL at 25 °C (lit.)

λ

H2O reference

UV absorption

λ: 235 nm Amax: 1.0
λ: 240 nm Amax: 0.10
λ: 250 nm Amax: 0.02
λ: 300-400 nm Amax: 0.005

SMILES string

ClCCl

InChI

1S/CH2Cl2/c2-1-3/h1H2

InChI key

YMWUJEATGCHHMB-UHFFFAOYSA-N

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General description

Dichloromethane is a polar and highly volatile organic compound (VOC), known for its versatile use in industries as an extraction solvent and metal cleaner and consumer products such as adhesives, spray shoe polishes, paint, and adhesive removers.

Application

Dichloromethane may be used in the following:

  • Extraction of neonicotinoids from honey samples along with acetonitrile using dispersive liquid-liquid microextraction (DLLME)
  • Ultrasonic solvent extraction and clean-up of roasted coffee samples for the analysis of 7 pesticide residues by liquid chromatography-tandem mass spectrometry (LC-MS/MS)
  • DLLME based additional pre-concentration of the sample extracts in the analysis of three amphenicols in food products of animal origin by HPLC with UV detection
  • Removal of organic phase of the obtained soil sample extracts in the determination of two sulfonylurea herbicides using HPLC
  • Testing of four extraction solvents in the development of a HPLC-amperometric detection based method for the analysis of three carbamate residues in liquid and solid food samples
  • Extraction of metrafenone from vegetable samples by matrix solid-phase dispersion (MSPD method followed by HPLC analysis

Suitable for HPLC, spectrophotometry, environmental testing

Other Notes

Pesticide Residue Analysis (as Heptachlor Epoxide) <10 ng/L
Pure-Pac® II containers require the Micromatic MacroValve coupler for dispensing solvents, Z560723.

Recommended products

Discover LiChropur reagents ideal for HPLC or LC-MS analysis

Legal Information

Pure-Pac is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Health hazardExclamation mark

signalword

Warning

Hazard Classifications

Carc. 2 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Central nervous system

Storage Class

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk_germany

WGK 2

flash_point_f

does not flash

flash_point_c

does not flash


Certificates of Analysis (COA)

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Jane A Mullaney et al.
Journal of agricultural and food chemistry, 61(12), 3039-3046 (2013-03-07)
Glucosinolates from the genus Brassica can be converted into bioactive compounds known to induce phase II enzymes, which may decrease the risk of cancers. Conversion via hydrolysis is usually by the brassica enzyme myrosinase, which can be inactivated by cooking
Matthew J Walters et al.
Nature protocols, 2(7), 1825-1830 (2007-07-21)
A procedure for the preparation of optically pure alpha-keto-gamma-hydroxy carboxylic acids through stereospecific aldol addition catalyzed by pyruvate aldolases from the Entner-Doudoroff and the DeLey-Doudoroff glycolytic pathways is described. This highly versatile fragment serves as a precursor for a variety
Vitamin B12-mediated hydrodechlorination of dichloromethane by bimetallic Cu/Al particles.
Huang CC, et al.
Chemical Engineering Journal, 273, 413-420 (2015)
Dichloromethane Detection Based on Near-Infrared Absorptive Sensing.
Han JH and Yoon SM
IEEE Journal of Selected Topics in Quantum Electronics, 18(5), 1547-1552 (2012)
Dichloromethane photodegradation using titanium catalysts.
Tanguay JF, et al.
Tanguay JF, et al.
J. Catal., 117(2), 335-347 (1989)

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