1510889

Perindopril erbumine

United States Pharmacopeia (USP) Reference Standard

• 同義詞: (2S,3aS,7aS)-1-[(2S)-2-[[(1S)-1-(ethoxycarbonyl)butyl]amino]-1-oxopropyl]octahydro-1H-indole-2-carboxylic acid tert-butylamine salt, S-9490
• 經驗公式（希爾表示法）: C₁₉H₃₂N₂O₅ · C₄H₁₁N
• CAS號碼: 107133-36-8
• 分子量：: 441.60
• MDL號碼: MFCD02313824
• 分類程式碼代碼: 41116107
• PubChem物質ID: 329750718
• NACRES: NA.24

屬性

• 等級: pharmaceutical primary standard
• API 家族: perindopril
• 製造商／商標名: USP
• 應用: pharmaceutical (small molecule)
• 形式: neat
• 儲存溫度: 2-8°C
• SMILES 字串: CC(C)(C)N.CCC[C@H](N[C@@H](C)C(=O)N1[C@H]2CCCC[C@H]2C[C@H]1C(O)=O)C(=O)OCC
• InChI: 1S/C19H32N2O5.C4H11N/c1-4-8-14(19(25)26-5-2)20-12(3)17(22)21-15-10-7-6-9-13(15)11-16(21)18(23)24;1-4(2,3)5/h12-16,20H,4-11H2,1-3H3,(H,23,24);5H2,1-3H3/t12-,13-,14-,15-,16-;/m0./s1
• InChI 密鑰: IYNMDWMQHSMDDE-MHXJNQAMSA-N
• 基因資訊: human ... ACE(1636)

描述

一般說明

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

應用

Perindopril erbumine USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Perindopril Erbumine Tablets

生化／生理作用

Perindopril erbumine is an angiotensin converting enzyme (ACE) inhibitor; antihypertensive.

Perindopril erbumine is an angiotensin converting enzyme (ACE) inhibitor; antihypertensive; becomes hydrolyzed in vivo to the active diacid metabolite; unlike the other ACE inhibitors, inhibits tumor growth in hepatocellular carcinoma cells due to suppression of VEGF levels; also suppresses angiotensin II production in vitro. Long-term therapy with this agent has a beneficial effect on the cerebral circulation by improving cerebral perfusion reserve in patients with previous minor stroke.

分析報告

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他說明

Sales restrictions may apply.

安全資訊

• 象形圖: GHS08
• 訊號詞: Warning
• 危險聲明: H361d
• 防範說明: P201 - P202 - P280 - P308 + P313 - P405 - P501
• 危險分類: Repr. 2
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable