推薦產品
product name
Astec® CHIROBIOTIC® T 手性 HPLC 色谱柱, 5 μm particle size, L × I.D. 25 cm × 4.6 mm
材料
stainless steel column
agency
suitable for USP L63
描述
HPLC column
產品線
Astec®
包裝
pkg of 1 ea
製造商／商標名
Astec®
參數
0-45 °C temperature
241 bar pressure (3500 psi)
技術
HPLC: suitable
LC/MS: suitable
長度 × 內徑
25 cm × 4.6 mm
基質
High-purity silica gel particle platform
fully porous particle
基質活性組
teicoplanin glycopeptide phase
粒徑
5 μm
孔徑
100 Å
工作pH值範圍
3.8-6.8
分離技術
chiral
尋找類似的產品？ 前往 產品比較指南
相關類別
一般說明
CHIROBIOTIC® T和T2具有替考拉宁作为手性选择剂。它们对许多类别的分子可提供独特的选择性，特别是未衍生化的α, β, γ以及环氨基酸、N-衍生氨基酸、羟基-羧基酸，酸性化合物包括羧基酸及酚、小肽、中性芳香族分析物及环状芳香族和脂肪族胺。通常在手性的冠醚或配体交换型CSP上获得的分离也可能发生在CHIROBIOTIC®T和T2上，但是是在大为简单的移动相如水-乙醇中。此外，所有已知的β-阻滞剂（氨醇）以及二氢香豆素都已被分解。CHIROBIOTIC® T和T2在它们的键化学和支持颗粒的孔径上存在差别，分别赋予了它们不同的选择和制备能力。
CHIROBIOTIC FAQ
CHIROBIOTIC 参考书目
Chiral产品文献
- 键合相：替考拉宁
- 操作pH范围：3.8 - 6.8
- 粒子直径：5、10或16 μm
- 孔径：100 Å (CHIROBIOTIC® T)或200 Å (CHIROBIOTIC® T2)
CHIROBIOTIC FAQ
CHIROBIOTIC 参考书目
Chiral产品文献
應用
- Chiral liquid chromatography-mass spectrometry (LC-MS/MS) method development for the detection of salbutamol in urine samples.: This study utilizes the Astec CHIROBIOTIC T Chiral HPLC Column to develop an LC-MS/MS method for detecting and quantifying salbutamol enantiomers in urine samples. This application demonstrates the column′s utility in biomedical and clinical research, particularly in the analysis of chiral drugs in biological matrices (Chan et al., 2016).
- High-performance liquid chromatographic enantioseparation of 2-aminomono- and dihydroxycyclopentanecarboxylic and 2-aminodihydroxycyclohexanecarboxylic acids on macrocyclic glycopeptide-based phases.: This research focuses on the enantioseparation of various amino acids using the Astec CHIROBIOTIC T Chiral HPLC Column, highlighting its effectiveness in separating complex chiral molecules. The study underscores the column′s application in the enantioselective analysis of amino acids and related compounds in chemical and pharmaceutical research (Berkecz et al., 2009).
法律資訊
Astec is a registered trademark of Merck KGaA, Darmstadt, Germany
CHIROBIOTIC is a registered trademark of Sigma-Aldrich Co. LLC
儲存類別代碼
13 - Non Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
客戶也查看了
Balázs Visegrády et al.
Journal of biochemical and biophysical methods, 53(1-3), 15-24 (2002-10-31)
This contribution deals with comparative studies on the chiral separation of thiazide diuretics using cellulose tris(3,5-dimethylphenylcarbamate) (Chiralcel OD-RH), cellulose tris(4-methylbenzoate) (Chiralcel OJ-R) and teicoplanin (Chirobiotic T) phases. All columns showed good chiral recognition ability for this class of compounds. Out
Zahid Ali et al.
Journal of chromatography. A, 1052(1-2), 199-204 (2004-11-06)
The solvation parameter model is used to characterize the retention properties of a 3-aminopropylsiloxane-bonded (Alltima amino), three 3-cyanopropylsiloxane-bonded (Ultrasphere CN, Ultremex-CN and Zorbax SB-CN), a spacer bonded propanediol (LiChrospher DIOL) and a multifunctional macrocyclic glycopeptide (Chirobiotic T) silica-based stationary phases
Felikss Mutulis et al.
Bioorganic & medicinal chemistry, 15(17), 5787-5810 (2007-07-10)
Two hundred and ten tertiary amides were prepared on solid phase. Diamines were coupled to activated carboxylated Wang polymer, and the polymeric substituted benzyloxycarbonyl protected diamines obtained were reacted with aldehydes or ketones in trimethyl orthoformate giving resin attached Schiff
B Mistry et al.
Journal of chromatography. B, Biomedical sciences and applications, 758(2), 153-161 (2001-08-07)
A sensitive and stereoselective high-performance liquid chromatographic assay for the determination of the enantiomers of metoprolol (R- and S-) and the diastereoisomers of alpha-hydroxymetoprolol (IIA, IIB) in plasma is reported. Chromatography involved direct separation of enantiomers using a Chirobiotic T
Syntheses of racemic and non-racemic silicon- and germanium-containing a-amino acids of the formula type H2NCH(CH2ElR3)COOH (El=Si, Ge; R=organyl) and incorporation of d-H2NCH(CH2SiMe3)COOH and d-H2NCH(CH2GeMe3)COOH into biologically active decapeptides: a study on C/Si/Ge bioisosterism
Merget, Markus, et al.
Journal of Organometallic Chemistry, 628 (2), 183-194 (2001)
相關內容
Astec CHIROBIOTIC™ T Chiral HPLC Columns - CHIROBIOTIC phases are based on covalently bonding macrocyclic glycoproteins to a high purity, spherical silica gel in such a way as to establish its stability while retaining essential components for chiral recognition.
Chromatograms
application for HPLCapplication for HPLCapplication for HPLCapplication for HPLC顯示更多我們的科學家團隊在所有研究領域都有豐富的經驗，包括生命科學、材料科學、化學合成、色譜、分析等.
聯絡技術服務