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Merck
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Key Documents

WH0001264M1

Sigma-Aldrich

Monoclonal Anti-CNN1 antibody produced in mouse

clone 2F5-1H4, purified immunoglobulin, buffered aqueous solution

同義詞:

Anti-SMCC, Anti-SmCalp, Anti-calponin 1, basic, smooth muscle

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

mouse

品質等級

共軛

unconjugated

抗體表格

purified immunoglobulin

抗體產品種類

primary antibodies

無性繁殖

2F5-1H4, monoclonal

形狀

buffered aqueous solution

物種活性

human

技術

indirect ELISA: suitable
western blot: 1-5 μg/mL

同型

IgG1κ

GenBank登錄號

UniProt登錄號

運輸包裝

dry ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... CNN1(1264)

免疫原

CNN1 (AAH22015, 1 a.a. ~ 297 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
MSSAHFNRGPAYGLSAEVKNKLAQKYDHQREQELREWIEGVTGRRIGNNFMDGLKDGIILCEFINKLQPGSVKKINESTQNWHQLENIGNFIKAITKYGVKPHDIFEANDLFENTNHTQVQSTLLALASMAKTKGNKVNVGVKYAEKQERKFEPGKLREGRNIIGLQMGTNKFASQQGMTAYGTRRHLYDPKLGTDQPLDQATISLQMGTNKGASQAGMTAPGTKRQIFEPGLGMEHCDTLNVSLQMGSNKGASQRGMTVYGLPRQVYDPKYCLTPEYPELGEPAHNHHAHNYYNSA

生化/生理作用

Calponin 1 (CNN1) plays a key role in regulation of smooth muscle contraction in various physiological situations. Measurement of CNN1 level in maternal serum is considered to be a potent method for the short-term prediction of preterm birth in women with threatened preterm labor. CNN1 also acts as a cardiac and smooth muscle differentiation marker. In addition, it is also implicated in the actomyosin stabilization and cell motility repression.

外觀

Solution in phosphate buffered saline, pH 7.4

法律資訊

GenBank is a registered trademark of United States Department of Health and Human Services

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


分析證明 (COA)

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存取文件庫

Maternal serum calponin 1 level as a biomarker for the short-term prediction of preterm birth in women with threatened preterm labor.
Cetin O
The Journal of Maternal-Fetal & Neonatal Medicine : The Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 31, 216-222 (2018)
Calponin1 inhibits dilated cardiomyopathy development in mice through the ?PKC pathway.
Lu D
International Journal of Cardiology, 173, 146-153 (2014)
Identification of the Critical Site of Calponin 1 for Suppression of Ovarian Cancer Properties.
Yamane T
Anticancer Research, 35, 5993-5999 (2015)

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