推薦產品
化驗
≥98% (HPLC)
形狀
powder
顏色
white to very faintly yellow
溶解度
DMSO: >15 mg/mL
起源
Allergan
儲存溫度
2-8°C
SMILES 字串
S1CCC(c2c1ccc(c2)C#Cc3ncc(cc3)C(=O)OCC)(C)C
InChI
1S/C21H21NO2S/c1-4-24-20(23)16-7-9-17(22-14-16)8-5-15-6-10-19-18(13-15)21(2,3)11-12-25-19/h6-7,9-10,13-14H,4,11-12H2,1-3H3
InChI 密鑰
OGQICQVSFDPSEI-UHFFFAOYSA-N
生化／生理作用
Tazarotene induces the expression of tazarotene-induced gene 3 (TIG3), a tumor suppressor gene.
Tazarotene induces the expression of tazarotene-induced gene 3 (TIG3), a tumor suppressor gene. It is a prodrug of tazarotenic acid, which specifically activates RARb and RARg, only weakly activates RARa, and is inactive at retinoid X receptors (RXRs). In psoriasis, tazarotene normalizes abnormal keratinocyte differentiation and reduces their hyperproliferation.
特點和優勢
This compound is a featured product for Gene Regulation research. Click here to discover more featured Gene Regulation products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound was developed by Allergan. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
訊號詞
Warning
危險聲明
危險分類
Repr. 2
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
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文章
We offer a variety of small molecule research tools, such as transcription factor modulators, inhibitors of chromatin modifying enzymes, and agonists/antagonists for target identification and validation in gene regulation research; a selection of these research tools is shown below.
我們提供各種小分子研究工具，例如轉錄因子調節劑、染色質修飾酵素的抑制劑，以及用於基因調控研究中靶點鑑定和驗證的激效劑/拮抗劑；以下是這些研究工具的精選。
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我們的科學家團隊在所有研究領域都有豐富的經驗，包括生命科學、材料科學、化學合成、色譜、分析等.
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