T2019

蒂巴因

powder

• 同義詞: Paramorphine
• 經驗公式（希爾表示法）: C₁₉H₂₁NO₃
• CAS號碼: 115-37-7
• 分子量：: 311.37
• EC號碼: 204-084-1
• MDL號碼: MFCD00027409
• 分類程式碼代碼: 12352200
• PubChem物質ID: 24900006
• NACRES: NA.77

屬性

• 形狀: powder
• 品質等級: 200
• 藥物控制: USDEA Schedule II; Home Office Schedule 2; stupéfiant (France); kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada; estupefaciente (Spain); Decreto Lei 15/93: Tabela IA (Portugal)
• 溶解度: alcohol: soluble 1 in 10 of alcohol; benzene: soluble 1 in 18 in benzene; chloroform: soluble 50 mg/ml, clear, yellow; diethyl ether: soluble 1 in 135 of ether; H₂O: insoluble
• SMILES 字串: [H][C@@]12Oc3c(OC)ccc4C[C@H]5N(C)CC[C@]1(C5=CC=C2OC)c34
• InChI: 1S/C19H21NO3/c1-20-9-8-19-12-5-7-15(22-3)18(19)23-17-14(21-2)6-4-11(16(17)19)10-13(12)20/h4-7,13,18H,8-10H2,1-3H3/t13-,18+,19+/m1/s1
• InChI 密鑰: FQXXSQDCDRQNQE-VMDGZTHMSA-N

描述

應用

Thebaine has been used for the synthesis of neopinone/codeinone ring systems[1]. Thebaine has also been used as a 1 mg/ml standard in methanol for urine thebaine analysis in individuals who had consumed poppy seeds[2].

生化／生理作用

The (-)-isomer of thebaine is the naturally-occurring constituent of opium that is a precursor of morphine. It has poor antinociceptive activity and induces convulsions. It binds to μ and δ opioid receptors in vitro.

外觀

Alkaloid powder

準備報告

Thebaine dissolves in chloroform at 50 mg/ml to yield a clear, yellow solution. It soluble in alcohol, ether, and benzene at 1:10, 1: 135, and 1:18 parts respectively. However, thebaine does not dissolve in water.

安全資訊

• 象形圖: GHS06
• 訊號詞: Danger
• 危險聲明: H301
• 防範說明: P264 - P270 - P301 + P310 - P405 - P501
• 危險分類: Acute Tox. 3 Oral
• 儲存類別代碼: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable
• 個人防護裝備: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges