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524980

Sigma-Aldrich

邻苯二甲酸二丁酯(驱蚊叮)

Dibutyl phthalate

99%

同義詞:

DBP, 正丁基邻苯二甲酸酯, 邻苯二甲酸二丁基酯

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About This Item

線性公式:
C6H4-1,2-[CO2(CH2)3CH3]2
CAS號碼:
分子量::
278.34
Beilstein:
1914064
EC號碼:
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22
化驗:
99%
bp:
340 °C (lit.)
蒸汽壓力:
1 mmHg ( 147 °C)
暫時無法取得訂價和供貨情況

蒸汽密度

9.6 (vs air)

品質等級

蒸汽壓力

1 mmHg ( 147 °C)

化驗

99%

形狀

liquid

自燃溫度

756 °F

expl. lim.

0.47 %, 236 °F

雜質

≤0.005% Acidity (as Phthalic acid)
≤0.15% water

顏色

APHA: ≤20

折射率

n20/D 1.492 (lit.)

pH值

7 (20 °C, 10 mg/L)

bp

340 °C (lit.)

mp

−35 °C (lit.)

密度

1.043 g/mL at 25 °C (lit.)

官能基

ester

SMILES 字串

CCCCOC(=O)c1ccccc1C(=O)OCCCC

InChI

1S/C16H22O4/c1-3-5-11-19-15(17)13-9-7-8-10-14(13)16(18)20-12-6-4-2/h7-10H,3-6,11-12H2,1-2H3

InChI 密鑰

DOIRQSBPFJWKBE-UHFFFAOYSA-N

基因資訊

mouse ... Esr1(13982)

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一般說明

邻苯二甲酸二丁酯(DBP)最常用作各种家用产品中的增塑剂。在使用或处理这些产品时,它可以浸出和蒸发到环境中。[1][2]因此,针对其毒性和细胞凋亡效应的研究正在进行。[1]研究还表明,接触高剂量的DBP可能会干扰黄体酮和雌二醇的产生。[2]

應用

增塑剂

象形圖

Health hazardEnvironment

訊號詞

Danger

危險聲明

危險分類

Aquatic Acute 1 - Aquatic Chronic 2 - Repr. 1B

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類(WGK)

WGK 3

閃點(°F)

367.7 °F - open cup

閃點(°C)

186.5 °C - open cup

個人防護裝備

Eyeshields, Gloves, type ABEK (EN14387) respirator filter


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分析證明 (COA)

Lot/Batch Number

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存取文件庫

Dibutyl phthalate impairs steroidogenesis and a subset of LH-dependent genes in cultured human mural granulosa cell in vitro.
Adir M
Reproductive Toxicology, 69, 13-18 (2017)
Dibutyl phthalate (DBP)-induced apoptosis and neurotoxicity are mediated via the aryl hydrocarbon receptor (AhR) but not by estrogen receptor alpha (ER?), estrogen receptor beta (ER?), or peroxisome proliferator-activated receptor gamma (PPAR?) in mouse cortical neurons.
Wojtowicz A
Neurotoxicity Research, 31(1), 77-89 (2017)
Damien Hunter et al.
International journal of molecular sciences, 22(8) (2021-05-01)
Xenobiotic exposure during pregnancy and lactation has been linked to perinatal changes in male reproductive outcomes and other endocrine parameters. This pilot study wished to assess whether brief maternal exposure of rats to xenobiotics dibutyl phthalate (DBP) or diethylstilbestrol (DES)
Linda V Sinclair et al.
Immunometabolism, 2(4), e200029-e200029 (2020-09-04)
Assays to monitor the metabolic state or nutrient uptake capacity of immune cells at a single cell level are increasingly in demand. One assay, used by many immunologists, employs 2-(N-(7-Nitrobenz-2-oxa-1,3-diazol-4-yl)Amino)-2-Deoxyglucose (2-NBDG), a fluorescent analogue of 2-deoxyglucose (2DG), as a substrate
Harpreet Bhatia et al.
Aquatic toxicology (Amsterdam, Netherlands), 149, 103-115 (2014-03-01)
Phthalic acid esters (PAEs) are a class of synthetic industrial chemicals commonly found in the aquatic environment worldwide. PAEs have been recognised as anti-androgens in male mammals but little is known about their endocrine disrupting effects in fish. This study

Questions

1–4 of 4 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  3. En que esta disuelto? a que concentración?

    1 answer
    1. This item is in liquid form with a purity of greater than or equal to 99.0%; it is not mixed with anything. Please see the sample Certificate of Anaylsis here: https://www.sigmaaldrich.com/certificates/sapfs/PROD/sap/certificate_pdfs/COFA/Q14/524980-BULKMKCV6253.pdf

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  4. Buenos días, Me gustaría confirmar si el formato "poly bottle" se trata de una botella de plástico y en su caso, si existe algún tipo de diferencia entre los formatos de 25 y 100 mL, puesto que la diferencia de precio es mínima.

    1 answer
    1. Item 524980-25ML is packaged in a HDPE plastic bottle and 524980-100ML is packaged in an amber glass bottle.

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我們的科學家團隊在所有研究領域都有豐富的經驗,包括生命科學、材料科學、化學合成、色譜、分析等.

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