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Merck
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重要文件

T1016

Sigma-Aldrich

Trichlormethiazide

≥98%

同義詞:

6-Chloro-3-(dichloromethyl)-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
(+/-)-, NSC 61560

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About This Item

經驗公式(希爾表示法):
C8H8Cl3N3O4S2
CAS號碼:
分子量::
380.66
EC號碼:
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:
NACRES:
NA.25
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化驗

≥98%

SMILES 字串

NS(=O)(=O)c1cc2c(NC(NS2(=O)=O)C(Cl)Cl)cc1Cl

InChI

1S/C8H8Cl3N3O4S2/c9-3-1-4-6(2-5(3)19(12,15)16)20(17,18)14-8(13-4)7(10)11/h1-2,7-8,13-14H,(H2,12,15,16)

InChI 密鑰

LMJSLTNSBFUCMU-UHFFFAOYSA-N

基因資訊

human ... SLC12A3(6559)

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象形圖

Health hazard

訊號詞

Danger

危險聲明

危險分類

Resp. Sens. 1 - Skin Sens. 1

儲存類別代碼

13 - Non Combustible Solids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


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Takeshi Takami
Hypertension research : official journal of the Japanese Society of Hypertension, 32(12), 1086-1090 (2009-09-26)
Morning hypertension has been reported to be an important risk factor for cardiovascular events, and arterial stiffness bears a relationship with cardiovascular risk. The aim of this study was to evaluate whether high-dose angiotensin II receptor blocker (ARB) treatment has
Haruo Mizuno et al.
Endocrine, 24(1), 55-59 (2004-07-14)
Congenital nephrogenic diabetes insipidus (NDI) is characterized by the insensitivity of the distal nephron to arginine vasopressin. Clinical knowledge of this disease is based largely on case reports. For this study, we investigated the clinical findings of eight patients in
Madori Osawa et al.
Pediatric nephrology (Berlin, Germany), 28(9), 1881-1884 (2013-05-22)
Four genes responsible for pseudohypoaldosteronism type II (PHA-II) have been identified, thereby facilitating molecular diagnostic testing. A 1-year-old boy with prolonged hyperkalemia, metabolic acidosis, hyperchloremia, growth delay, and mild hypertension was diagnosed with PHA-II based on the detection of exon
Yasuo Takahashi et al.
Cardiovascular diabetology, 10, 45-45 (2011-05-25)
Trichlormethiazide, a thiazide diuretic, was introduced in 1960 and remains one of the most frequently used diuretics for treating hypertension in Japan. While numerous clinical trials have indicated important side effects of thiazides, e.g., adverse effects on electrolytes and uric
Osamu Ito et al.
Hypertension research : official journal of the Japanese Society of Hypertension, 26(6), 509-513 (2003-07-17)
Exercise-induced acute renal failure (ARF) developed in a 45-year-old man during antihypertensive therapy with losartan and trichlormethiazide. The antihypertensive therapy was stopped and marked hypouricemia became apparent during improvement of his renal function. The daily urinary excretion of uric acid

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