SRP8044

CD40L, Soluble human

recombinant, expressed in CHO cells, FLAG^® tagged, >95% (SDS-PAGE)

• 同義詞: ACRP30headless:CD154, ACRP30headless:CD40L, ACRP30headless:TNFSF5, ADIPOQ-CD40L
• 分類程式碼代碼: 12352200
• NACRES: NA.77

屬性

• 生物源: human
• 重組細胞: expressed in CHO cells
• 籤條: FLAG^® tagged
• 化驗: >95% (SDS-PAGE)
• 形狀: lyophilized
• 分子量: 35-40 kDa by SDS-PAGE
• 包裝: pkg of 10 μg
• 儲存條件: avoid repeated freeze/thaw cycles
• 雜質: <0.01 EU/μg endotoxin, tested
• UniProt登錄號: P29965
• 運輸包裝: wet ice
• 儲存溫度: −20°C
• 基因資訊: human ... CD40LG(959)

描述

一般說明

CD40L (cluster of differentiation 40 ligand) belongs to the tumor necrosis factor (TNF) family, and is expressed by basophils, B cells, monocytic cells, natural killer cells, platelets, mast cells and T cells. It is predominantly expressed on pro-inflammatory T cells. It also exists in a soluble form.[1]

生化／生理作用

CD40L (cluster of differentiation 40 ligand) is active in its membrane-bound form.[1] It interacts with CD40 and functions as a proinflammatory and procoagulant agent. The serum levels of soluble CD40L is elevated in malignant middle cerebral artery infarction (MMCAI) patients, especially in non-surviving patients.[2]

外觀

Lyophilized from PBS

重構

Reconstitute with 100 μL deionized water.

其他說明

Human CD40L (aa 116-261) is fused at the N-terminus to mouse ACRP30headless (aa 18-111) and a FLAG^®-tag.

法律資訊

FLAG is a registered trademark of Merck KGaA, Darmstadt, Germany

安全資訊

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable