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Merck
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重要文件

SRP3287

Sigma-Aldrich

IL-34 human

recombinant, expressed in HEK 293 cells, ≥95% (SDS-PAGE), ≥95% (HPLC)

同義詞:

C16orf77

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About This Item

分類程式碼代碼:
12352202
NACRES:
NA.32
暫時無法取得訂價和供貨情況

生物源

human

重組細胞

expressed in HEK 293 cells

化驗

≥95% (HPLC)
≥95% (SDS-PAGE)

形狀

lyophilized

分子量

52.5 kDa

包裝

pkg of 10 μg

雜質

<0.1 EU/μg endotoxin, tested

UniProt登錄號

運輸包裝

wet ice

儲存溫度

−20°C

基因資訊

human ... IL34(146433)

一般說明

IL-34 is a ligand for colony-stimulating factor-1 receptor (CSF1R), which also binds to CSF-1. It specifically binds CD14+ monocytes, promotes survival and proliferation of human peripheral blood monocytes, and stimulates macrophage colony formation by human bone marrow cells. IL-34, like human CSF-1 stimulates phosphorylation of MAPK1/ERK2 and MAPK3/ERK1.

生化/生理作用

IL-34 is a homodimeric cytokine that is expressed in a range of tissues including spleen, heart, brain, liver, kidney, lung, ovary, thymus, testis, small intestine, prostate and colon. Recombinant human IL-34 is a 52.5 kDa homodimeric glycoprotein consisting of 460 amino acid residues, including a C-terminal His-Tag.

外觀

Lyophilized from 20 mM Sodium Citrate, pH 3.0 + 75 mM NaCl.

重構

Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/mL. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Eye Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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