推薦產品
品質等級
化驗
≥98% (HPLC)
形狀
powder
顏色
white to beige
溶解度
DMSO: 2 mg/mL, clear
儲存溫度
2-8°C
SMILES 字串
O=C1OC(C(C2=CC3=C(S2)C=CC=C3)=C1Br)O
生化／生理作用
CAY10526 is a selective inhibitor of microsomal prostaglandin E2 synthase-1 (mPGES-1) expression. CAY10526 potently inhibits PGE2 production in lipopolysaccharide-stimulated RAW 264.7 cells. CAY10526 significantly suppressed tumor growth and increased apoptosis in melanoma xenografts.
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。
Darren J Perkins et al.
Nature immunology, 19(12), 1309-1318 (2018-11-07)
The unique cell biology of Toll-like receptor 4 (TLR4) allows it to initiate two signal-transduction cascades: a signal dependent on the adaptors TIRAP (Mal) and MyD88 that begins at the cell surface and regulates proinflammatory cytokines, and a signal dependent
Sun-Hee Kim et al.
Pigment cell & melanoma research, 29(3), 297-308 (2016-01-24)
COX-2 and its product PGE2 enhance carcinogenesis and tumor progression, which has been previously reported in melanoma. As most COX inhibitors cause much toxicity, the downstream microsomal PGE2 synthase-1 (mPGES1) is a consideration for targeting. Human melanoma TMAs were employed
Maria D Guerrero et al.
Journal of medicinal chemistry, 50(9), 2176-2184 (2007-04-05)
As a part of our drug discovery effort, recently we clarified the molecular basis of phospholipase A2 (PLA2) inactivation by petrosaspongiolide M (PM), an interesting metabolite belonging to a marine sesterterpene family, containing in its structural architecture a gamma-hydroxybutenolide moiety
我們的科學家團隊在所有研究領域都有豐富的經驗，包括生命科學、材料科學、化學合成、色譜、分析等.
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