SML1450

Isobavachalcone

≥98% (HPCE)

• 同義詞: (2E)-1-[2,4-Dihydroxy-3-(3-methyl-2-butenyl)phenyl]-3-(4-hydroxyphenyl)-2-propen-1-one, 2′,4,4′-Trihydroxy-3′-(3-methyl-2-butenyl)-chalcone, Corylifolinin, Isobacachalcone
• 經驗公式（希爾表示法）: C₂₀H₂₀O₄
• CAS號碼: 20784-50-3
• 分子量：: 324.37
• MDL號碼: MFCD00902090
• 分類程式碼代碼: 12352200
• PubChem物質ID: 329825889
• NACRES: NA.77

屬性

• 品質等級: 100
• 化驗: ≥98% (HPCE)
• 形狀: powder
• 儲存條件: desiccated; protect from light
• 顏色: white to beige
• 溶解度: DMSO: 5 mg/mL, clear (warmed)
• 儲存溫度: −20°C
• SMILES 字串: OC1=C(CC=C(C)C)C(O)=C(C(/C=C/C2=CC=C(O)C=C2)=O)C=C1
• InChI: 1S/C20H20O4/c1-13(2)3-9-16-19(23)12-10-17(20(16)24)18(22)11-6-14-4-7-15(21)8-5-14/h3-8,10-12,21,23-24H,9H2,1-2H3/b11-6+
• InChI 密鑰: DUWPGRAKHMEPCM-IZZDOVSWSA-N

描述

生化／生理作用

Isobavachalcone is a chalcone isolated from multipurpose medical plant Psoralea corylifolia that inhibits LPS-induced ICAM-1 expression and leukocyte adhesion to brain endothelial cells. It appears that isobavachalcone modulates both MyD88-dependent and TRIF-dependent signaling of toll-like receptor 4 (TLR4). Isobavachalcone significantly inhibits both oligomerization and fibrillization of Aβ42. Isobavachalcone exhibits a wide spectrum of biological activities including antioxidative, antiplatelet, antimicrobial, anti-inflammatory, antitumor, and neuroprotective.

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable