推薦產品
品質等級
化驗
≥97% (HPLC)
形狀
powder
儲存條件
desiccated
顏色
white to beige
溶解度
H2O: 10 mg/mL, clear
儲存溫度
−20°C
InChI
1S/C24H35N7.3ClH/c1-6-31(7-2)12-8-9-16(3)27-24-28-18(5)14-23(30-24)29-19-10-11-22-20(15-19)21(25)13-17(4)26-22;;;/h10-11,13-16H,6-9,12H2,1-5H3,(H2,25,26)(H2,27,28,29,30);3*1H
InChI 密鑰
CPUHORIUXPQCHW-UHFFFAOYSA-N
應用
NSC23766 三盐酸盐已被用作 ras 相关的 C3 肉毒毒素底物 1 (RAC1) 抑制剂。
生化／生理作用
NSC23766 是一种 Rac1 抑制剂，一种 Rho 家族 gtp 酶。该化合物通过鸟嘌呤核苷酸交换因子 Trio 和 Tiam1 阻断活化，但不影响与 RhoA 或 Cdc42 的相互作用。NSC23766 阻断 ADP 介导的血小板聚集。NSC23766 对 Rac1 的抑制通过恢复 ErbB2 的下调恢复曲妥珠单抗的敏感性。
特點和優勢
该化合物是环核苷酸研究的特色产品。 点击此处 ，发现更多特色环核苷酸产品。前往 sigma.com/discover-bsm了解更多关于其他研究领域的生物活性小分子。
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。
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