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Merck
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重要文件

SML0739

Sigma-Aldrich

TAPI-1 acetate salt

≥97% (HPLC)

同義詞:

N-[(2R)-2-[2-(Hydroxyamino)-2-oxoethyl]-4-methyl-1-oxopentyl]-3-(2-naphthalenyl)-L-alanyl-N-(2-aminoethyl)-L-Alaninamide acetate salt

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About This Item

經驗公式(希爾表示法):
C26H37N5O5 · xC2H4O2
CAS號碼:
分子量::
499.60 (free base basis)
分類程式碼代碼:
12352200
NACRES:
NA.77
暫時無法取得訂價和供貨情況

化驗

≥97% (HPLC)

形狀

powder

顏色

white to beige

運輸包裝

wet ice

儲存溫度

−20°C

SMILES 字串

N(O)C(=O)C[C@@H](CC(C)C)C(=O)N[C@@H](Cc1cc2c(cc1)cccc2)C(=O)N[C@@H](C)C(=O)NCCN

InChI

1S/C26H37N5O5/c1-16(2)12-21(15-23(32)31-36)25(34)30-22(26(35)29-17(3)24(33)28-11-10-27)14-18-8-9-19-6-4-5-7-20(19)13-18/h4-9,13,16-17,21-22,36H,10-12,14-15,27H2,1-3H3,(H,28,33)(H,29,35)(H,30,34)(H,31,32)/t17-,21+,22-/m0/s1

InChI 密鑰

AWNBSWDIOCXWJW-WTOYTKOKSA-N

應用

TAPI-1 acetate salt has been used as a tumor necrosis factor(TNF)-α convertase/ADAM17/α-secretase (TACE) inhibitor.[1][2][3]

生化/生理作用

TAPI-1 is a potent inhibitor of matrix metalloproteinases and TACE (TNF-α convertase/ADAM17/α-secretase).
TAPI-1 is a potent inhibitor of matrix metalloproteinases and TACE.

象形圖

Skull and crossbones

訊號詞

Danger

危險聲明

危險分類

Acute Tox. 3 Oral

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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