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About This Item
經驗公式(希爾表示法):
C18H32O3
CAS號碼:
分子量::
296.44
EC號碼:
MDL號碼:
分類程式碼代碼:
51111800
PubChem物質ID:
NACRES:
NA.77
暫時無法取得訂價和供貨情況
推薦產品
品質等級
化驗
≥98% (HPLC)
形狀
solution
濃度
1 mg/mL in ethanol
顏色
colorless to light yellow
運輸包裝
wet ice
儲存溫度
−20°C
SMILES 字串
CCCCC/C=C\C=C\[C@@H](O)CCCCCCCC(O)=O
InChI
1S/C18H32O3/c1-2-3-4-5-6-8-11-14-17(19)15-12-9-7-10-13-16-18(20)21/h6,8,11,14,17,19H,2-5,7,9-10,12-13,15-16H2,1H3,(H,20,21)/b8-6-,14-11+/t17-/m1/s1
InChI 密鑰
NPDSHTNEKLQQIJ-UINYOVNOSA-N
生化/生理作用
9(S)-HODE是一种促炎性亚油酸脂氧化产物。
9(S)-HODE由亚油酸脂氧化反应生成。它是血浆氧化低密度脂蛋白的主要成分。 9-HODE经证可以通过PPARgamma刺激人系膜细胞的细胞增殖和细胞外基质合成。 9-HODE的促炎效果通过受体GPR132起作用,可促进动脉粥样硬化的进展。9-HODE还经证可以激活脊髓TRPV1,导致炎症性痛觉过敏。
訊號詞
Danger
危險聲明
危險分類
Eye Irrit. 2 - Flam. Liq. 2
儲存類別代碼
3 - Flammable liquids
水污染物質分類(WGK)
WGK 1
閃點(°F)
57.2 °F - closed cup
閃點(°C)
14.0 °C - closed cup
從最近期的版本中選擇一個:
Shasha Li et al.
Scientific reports, 8(1), 14627-14627 (2018-10-04)
Zhenwu decoction (ZWD) is a promising traditional Chinese prescription against renal fibrosis, while its underlying mechanism remains unclear. Rat model of renal fibrosis were established and divided into control group, model group, ZWD treatment group and enalapril maleate treatment group.
Edgar B Cahoon et al.
The Journal of biological chemistry, 279(13), 12495-12502 (2004-01-14)
Dimorphecolic acid (9-OH-18:2Delta(10)(trans)(,12)(trans)) is the major fatty acid of seeds of Dimorphotheca species. This fatty acid contains structural features that are not typically found in plant fatty acids, including a C-9 hydroxyl group, Delta(10),Delta(12)-conjugated double bonds, and trans-Delta(12) unsaturation. Expressed
Markus K Muellner et al.
The Biochemical journal, 420(2), 277-281 (2009-03-07)
LOOHs (lipid hydroperoxides) in oxLDL [oxidized LDL (low-density lipoprotein)] are potentially atherogenic compounds. Recently, H2S was identified as the third endogenous gasotransmitter in the vasculature. H2O2 is known to be destroyed by H2S. Assuming that H2S may also react with
Frédéric Coutant et al.
Journal of immunology (Baltimore, Md. : 1950), 172(1), 54-60 (2003-12-23)
Because of its oxidative modification during the acute-phase response to an aggression, low density lipoprotein (LDL) can be regarded as a source of lipid mediators that can act both to promote and inhibit inflammation. This can be exemplified by the
N Marx et al.
Arteriosclerosis, thrombosis, and vascular biology, 19(3), 546-551 (1999-03-12)
Plasminogen activator inhibitor type-1 (PAI-1) is a major physiological inhibitor of fibrinolysis, with its plasma levels correlating with the risk for myocardial infarction and venous thrombosis. The regulation of PAI-1 transcription by endothelial cells (ECs), a major source of PAI-1
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