SML0180

乙酰甲啶 盐酸盐

≥98% (HPLC)

• 同義詞: 1-Azabicyclo[2.2.2]oct-3-yl acetate hydrochloride, 3-Acetoxyquinuclidine hydrochloride
• 經驗公式（希爾表示法）: C₉H₁₅NO₂ · HCl
• CAS號碼: 6109-70-2
• 分子量：: 205.68
• EC號碼: 228-071-5
• 分類程式碼代碼: 12352200
• PubChem物質ID: 329825209
• NACRES: NA.77

屬性

• 化驗: ≥98% (HPLC)
• 形狀: powder
• 儲存條件: desiccated
• 顏色: white to tan
• 溶解度: H₂O: ≥15 mg/mL at ~60 °C
• 儲存溫度: −20°C
• SMILES 字串: Cl.CC(=O)O[C@H]1CN2CC[C@H]1CC2
• InChI: 1S/C9H15NO2.ClH/c1-7(11)12-9-6-10-4-2-8(9)3-5-10;/h8-9H,2-6H2,1H3;1H/t9-;/m0./s1
• InChI 密鑰: LWWSARSTZGNKGV-FVGYRXGTSA-N

描述

應用

Aceclidine hydrochloride may be used in muscarinic acetylcholine receptor-mediated cell signaling studies.

生化／生理作用

Aceclidine at a concentration of 5 and 50 μg is capable of enhancing the outflow facility, following ciliary muscle disinsertion.[1]

Aceclidine hydrochloride is a parasympathomimetic drug with weak anticholinesterase activity. It acts on cholinergic nerve-endings, lowers intraocular pressure and potent therapeutic agent for open-angle glaucoma.[2]

Aceclidine is a non-selective muscarinic acetylcholine receptor partial agonist that is effective in reducing intraocular pressure.

Muscarinic receptor partial agonist

特點和優勢

This compound is featured on the Acetylcholine Receptors (Muscarinic) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

安全資訊

• 象形圖: GHS06
• 訊號詞: Danger
• 危險聲明: H301 + H311
• 防範說明: P264 - P280 - P301 + P310 - P302 + P352 + P312 - P361 + P364 - P405
• 危險分類: Acute Tox. 3 Dermal - Acute Tox. 3 Oral
• 儲存類別代碼: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable