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Merck
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重要文件

SMB00113

Sigma-Aldrich

6-Geranyl-7-hydroxycoumarin

≥95% (LC/MS-ELSD)

同義詞:

6-(3,7-Dimethyl-2,6-octadienyl)-7-hydroxycoumarin, Ostruthin, Ostruthine

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About This Item

經驗公式(希爾表示法):
C19H22O3
CAS號碼:
分子量::
298.38
MDL號碼:
分類程式碼代碼:
12352205
PubChem物質ID:
NACRES:
NA.25
暫時無法取得訂價和供貨情況

化驗

≥95% (LC/MS-ELSD)

形狀

solid

應用

metabolomics
vitamins, nutraceuticals, and natural products

儲存溫度

−20°C

SMILES 字串

C\C(C)=C\CC\C(C)=C\Cc1cc2C=CC(=O)Oc2cc1O

InChI

1S/C19H22O3/c1-13(2)5-4-6-14(3)7-8-15-11-16-9-10-19(21)22-18(16)12-17(15)20/h5,7,9-12,20H,4,6,8H2,1-3H3/b14-7+

InChI 密鑰

INBMTJJPUABOQJ-VGOFMYFVSA-N

一般說明

Natural product derived from plant source.

象形圖

Environment

訊號詞

Warning

危險聲明

防範說明

危險分類

Aquatic Acute 1 - Aquatic Chronic 1

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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分析證明 (COA)

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J Qi et al.
Bioscience, biotechnology, and biochemistry, 63(8), 1501-1502 (1999-09-29)
A search for neuritogenic compounds in Chinese herbs resulted in the isolation of two known substances, ostruthin and (-)-bornyl ferulate, from Notopterygium incisum (and/or N. forbesii). Both compounds induced comparable neurite-like structures in 20% of rat PC12 cells at 2
Andreas Schinkovitz et al.
Planta medica, 69(4), 369-371 (2003-04-24)
Following a bioassay-guided fractionation, ostruthin (6-geranyl-7-hydroxycoumarin) was isolated from the roots of Peucedanum ostruthium Koch (Apiaceae) as a compound with pronounced in vitro activity against several species of rapidly growing Mycobacteria, namely Mycobacterium abscesus, M. aurum, M. fortuitum, M. phlei
Helge Joa et al.
Journal of natural products, 74(6), 1513-1516 (2011-06-02)
Inhibition of vascular smooth muscle cell (VSMC) proliferation is of substantial interest in combating cardiovascular disease. A dichloromethane extract from the rhizomes of Peucedanum ostruthium, a traditionally used Austrian medicinal plant with anti-inflammatory properties, was examined for a putative antiproliferative
Feng Li et al.
Planta medica, 78(8), 796-799 (2012-04-21)
During a search for potent anticancer agents from natural products based on an anti-austerity strategy, we found that a CHCl3 extract of Rhizoma et Radix Notopterygii (Qianghuo), a Chinese crude drug, exhibited strong cytotoxicity against PANC-1 human pancreatic cancer cells
Y Cai et al.
Carcinogenesis, 18(8), 1521-1527 (1997-08-01)
Several naturally occurring coumarins previously found to be potent inhibitors of mouse hepatic ethoxyresorufin-O-deethylase (EROD) and/or pentoxyresorufin-O-dealkylase (PROD) were examined for their effects on formation of benzo[a]pyrene (B[a]P) and 7,12-dimethylbenz[a]anthracene (DMBA) DNA adducts in mouse epidermis, as well as, their

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